GSM8077630

Dataset: gse255685 • Sample: Z292 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 0.5%ile (↓ Low)
22,319 Genes with score > 0 Group median: 22,381 • 0.9%ile (↓ Low)
0 Median expression score Group median: 0 • 2.0%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

36.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.03
bar=donor   line=cohort median 		2.02 51.1%
FOXO3 Insulin/IGF-1 Signaling 9.70
bar=donor   line=cohort median 		9.99 14.5%
CETP Lipid Metabolism 4.71
bar=donor   line=cohort median 		5.05 14.2%
SIRT6 Sirtuin Family 8.20
bar=donor   line=cohort median 		8.34 18.1%
SIRT1 Sirtuin Family 9.13
bar=donor   line=cohort median 		8.72 99.5%
SIRT3 Sirtuin Family 6.99
bar=donor   line=cohort median 		7.49 1.3%
IGF1R Insulin/IGF-1 Signaling 9.85
bar=donor   line=cohort median 		10.21 20.6%
KLOTHO Anti-aging 2.77
bar=donor   line=cohort median 		2.51 83.7%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 11.7%
IL6 Inflammation 1.06
bar=donor   line=cohort median 		1.16 21.0%
TERT Telomere Maintenance 1.34
bar=donor   line=cohort median 		1.51 13.1%
IRS2 Insulin/IGF-1 Signaling 9.44
bar=donor   line=cohort median 		9.81 17.0%
TP53 Tumor Suppression 9.07
bar=donor   line=cohort median 		8.92 74.0%
SHC1 Signal Transduction 9.33
bar=donor   line=cohort median 		9.35 41.0%
ACE Signal Transduction 4.75
bar=donor   line=cohort median 		4.64 62.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.3 0
3 EEF1A1 17.1 0
4 ACTB 16.6 0
5 MT-CO1 16.5 0
6 HLA-C 16.0 0
7 MT-RNR1 15.9 0
8 HLA-B 15.9 0
9 S100A9 15.8 0
10 MT-ND4 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.6
bar=donor   line=cohort median 		14.4 14.2 75.8%
2 S100A9 15.8
bar=donor   line=cohort median 		15.8 15.5 72.9%
3 IL1B 9.6
bar=donor   line=cohort median 		8.8 9.3 64.7%
4 CXCL8 12.0
bar=donor   line=cohort median 		12.2 11.4 67.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.3
bar=donor   line=cohort median 		6.1 6.1 2.0%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.7 14.7 55.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.7
bar=donor   line=cohort median 		14.3 14.3 81.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.6 10.4 83.0%
9 CD3E 12.4
bar=donor   line=cohort median 		12.1 12.0 93.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.8 10.9 61.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 74.7%
12 GNLY 12.8
bar=donor   line=cohort median 		12.4 12.1 86.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 74.7%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 62.5%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 55.0%
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