GSM8077632

Dataset: gse255685 • Sample: Z294 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 14.5%ile (↓ Low)
22,350 Genes with score > 0 Group median: 22,381 • 14.5%ile (↓ Low)
0 Median expression score Group median: 0 • 16.7%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

56.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.17
bar=donor   line=cohort median 		2.02 74.4%
FOXO3 Insulin/IGF-1 Signaling 10.00
bar=donor   line=cohort median 		9.99 51.4%
CETP Lipid Metabolism 5.14
bar=donor   line=cohort median 		5.05 65.1%
SIRT6 Sirtuin Family 8.24
bar=donor   line=cohort median 		8.34 27.1%
SIRT1 Sirtuin Family 9.08
bar=donor   line=cohort median 		8.72 98.4%
SIRT3 Sirtuin Family 7.38
bar=donor   line=cohort median 		7.49 32.1%
IGF1R Insulin/IGF-1 Signaling 10.35
bar=donor   line=cohort median 		10.21 67.9%
KLOTHO Anti-aging 3.06
bar=donor   line=cohort median 		2.51 98.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 51.1%
IL6 Inflammation 1.09
bar=donor   line=cohort median 		1.16 32.8%
TERT Telomere Maintenance 1.46
bar=donor   line=cohort median 		1.51 40.3%
IRS2 Insulin/IGF-1 Signaling 9.45
bar=donor   line=cohort median 		9.81 17.7%
TP53 Tumor Suppression 9.10
bar=donor   line=cohort median 		8.92 78.7%
SHC1 Signal Transduction 9.28
bar=donor   line=cohort median 		9.35 25.3%
ACE Signal Transduction 5.05
bar=donor   line=cohort median 		4.64 85.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.0 0
3 EEF1A1 16.7 0
4 MT-CO1 16.5 0
5 ACTB 16.4 0
6 MT-RNR1 16.0 0
7 HLA-C 16.0 0
8 HLA-B 16.0 0
9 HLA-E 15.7 0
10 MT-ND4 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 53.2%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 37.1%
3 IL1B 9.4
bar=donor   line=cohort median 		8.8 9.3 54.7%
4 CXCL8 11.4
bar=donor   line=cohort median 		12.2 11.4 48.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 31.7%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 68.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.3
bar=donor   line=cohort median 		14.3 14.3 47.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 35.3%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 32.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		10.8 10.9 83.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.2
bar=donor   line=cohort median 		12.2 11.7 11.3%
12 GNLY 11.8
bar=donor   line=cohort median 		12.4 12.1 27.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 61.1%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 59.7%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 71.9%
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