GSM8077633

Dataset: gse255685 • Sample: Z299 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 3.8%ile (↓ Low)
22,324 Genes with score > 0 Group median: 22,381 • 2.0%ile (↓ Low)
0 Median expression score Group median: 0 • 3.8%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.80
bar=donor   line=cohort median 		2.02 13.8%
FOXO3 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.99 64.3%
CETP Lipid Metabolism 4.85
bar=donor   line=cohort median 		5.05 26.7%
SIRT6 Sirtuin Family 7.81
bar=donor   line=cohort median 		8.34 0.2%
SIRT1 Sirtuin Family 9.15
bar=donor   line=cohort median 		8.72 99.8%
SIRT3 Sirtuin Family 7.48
bar=donor   line=cohort median 		7.49 48.2%
IGF1R Insulin/IGF-1 Signaling 10.34
bar=donor   line=cohort median 		10.21 66.1%
KLOTHO Anti-aging 2.58
bar=donor   line=cohort median 		2.51 62.2%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 46.1%
IL6 Inflammation 1.33
bar=donor   line=cohort median 		1.16 81.5%
TERT Telomere Maintenance 1.37
bar=donor   line=cohort median 		1.51 19.2%
IRS2 Insulin/IGF-1 Signaling 9.54
bar=donor   line=cohort median 		9.81 24.6%
TP53 Tumor Suppression 9.14
bar=donor   line=cohort median 		8.92 85.5%
SHC1 Signal Transduction 9.31
bar=donor   line=cohort median 		9.35 36.4%
ACE Signal Transduction 4.29
bar=donor   line=cohort median 		4.64 15.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 17.0 0
3 EEF1A1 16.8 0
4 ACTB 16.5 0
5 MT-CO1 16.4 0
6 MT-RNR1 16.1 0
7 HLA-C 15.8 0
8 HLA-B 15.6 0
9 HLA-E 15.6 0
10 FTL 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 49.6%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 38.9%
3 IL1B 9.5
bar=donor   line=cohort median 		8.8 9.3 64.0%
4 CXCL8 9.5
bar=donor   line=cohort median 		12.2 11.4 19.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 27.1%
6 FCGR3B 15.2
bar=donor   line=cohort median 		14.7 14.7 88.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 87.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.6 10.4 43.2%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 27.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.8 10.9 89.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.3
bar=donor   line=cohort median 		12.2 11.7 17.4%
12 GNLY 11.8
bar=donor   line=cohort median 		12.4 12.1 28.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 38.9%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.6 15.3 19.5%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 51.4%
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