GSM8077635

Dataset: gse255685 • Sample: Z502 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 81.9%ile (↑ High)
22,368 Genes with score > 0 Group median: 22,381 • 35.7%ile (≈ Median)
0 Median expression score Group median: 0 • 13.1%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

58.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.29
bar=donor   line=cohort median 		2.02 81.9%
FOXO3 Insulin/IGF-1 Signaling 10.35
bar=donor   line=cohort median 		9.99 93.0%
CETP Lipid Metabolism 4.86
bar=donor   line=cohort median 		5.05 29.2%
SIRT6 Sirtuin Family 8.84
bar=donor   line=cohort median 		8.34 96.6%
SIRT1 Sirtuin Family 8.38
bar=donor   line=cohort median 		8.72 9.9%
SIRT3 Sirtuin Family 7.52
bar=donor   line=cohort median 		7.49 56.5%
IGF1R Insulin/IGF-1 Signaling 10.20
bar=donor   line=cohort median 		10.21 49.3%
KLOTHO Anti-aging 2.57
bar=donor   line=cohort median 		2.51 60.8%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 91.2%
IL6 Inflammation 1.04
bar=donor   line=cohort median 		1.16 18.1%
TERT Telomere Maintenance 1.76
bar=donor   line=cohort median 		1.51 88.7%
IRS2 Insulin/IGF-1 Signaling 11.30
bar=donor   line=cohort median 		9.81 99.1%
TP53 Tumor Suppression 8.38
bar=donor   line=cohort median 		8.92 3.1%
SHC1 Signal Transduction 9.44
bar=donor   line=cohort median 		9.35 76.5%
ACE Signal Transduction 4.40
bar=donor   line=cohort median 		4.64 27.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.7 0
3 HLA-C 17.4 0
4 ACTB 17.2 0
5 S100A9 17.1 0
6 HLA-B 17.0 0
7 EEF1A1 16.9 0
8 FTL 16.7 0
9 HLA-E 16.5 0
10 MT-CO1 16.4 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.6
bar=donor   line=cohort median 		14.4 14.2 98.7%
2 S100A9 17.1
bar=donor   line=cohort median 		15.8 15.5 99.1%
3 IL1B 9.2
bar=donor   line=cohort median 		8.8 9.3 44.6%
4 CXCL8 14.1
bar=donor   line=cohort median 		12.2 11.4 99.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.2
bar=donor   line=cohort median 		6.1 6.1 62.2%
6 FCGR3B 15.4
bar=donor   line=cohort median 		14.7 14.7 94.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.0
bar=donor   line=cohort median 		14.3 14.3 20.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 75.1%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 59.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 9.9
bar=donor   line=cohort median 		10.8 10.9 0.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.9
bar=donor   line=cohort median 		12.2 11.7 61.5%
12 GNLY 12.0
bar=donor   line=cohort median 		12.4 12.1 43.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 48.2%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.6 15.3 84.4%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 71.1%
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