GSM8077636

Dataset: gse255685 • Sample: Z507 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 85.1%ile (↑ High)
22,391 Genes with score > 0 Group median: 22,381 • 69.2%ile (≈ Median)
0 Median expression score Group median: 0 • 66.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.00
bar=donor   line=cohort median 		2.02 47.5%
FOXO3 Insulin/IGF-1 Signaling 9.65
bar=donor   line=cohort median 		9.99 10.6%
CETP Lipid Metabolism 5.15
bar=donor   line=cohort median 		5.05 65.4%
SIRT6 Sirtuin Family 8.56
bar=donor   line=cohort median 		8.34 84.1%
SIRT1 Sirtuin Family 8.65
bar=donor   line=cohort median 		8.72 42.8%
SIRT3 Sirtuin Family 7.71
bar=donor   line=cohort median 		7.49 84.8%
IGF1R Insulin/IGF-1 Signaling 9.72
bar=donor   line=cohort median 		10.21 11.3%
KLOTHO Anti-aging 2.28
bar=donor   line=cohort median 		2.51 15.2%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 90.5%
IL6 Inflammation 1.27
bar=donor   line=cohort median 		1.16 70.1%
TERT Telomere Maintenance 1.45
bar=donor   line=cohort median 		1.51 37.5%
IRS2 Insulin/IGF-1 Signaling 9.67
bar=donor   line=cohort median 		9.81 35.0%
TP53 Tumor Suppression 8.89
bar=donor   line=cohort median 		8.92 48.2%
SHC1 Signal Transduction 9.31
bar=donor   line=cohort median 		9.35 36.7%
ACE Signal Transduction 3.85
bar=donor   line=cohort median 		4.64 0.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.0 0
2 B2M 17.3 0
3 EEF1A1 16.9 0
4 ACTB 16.8 0
5 MT-RNR1 16.7 0
6 MT-CO1 16.6 0
7 FKBP8 16.5 0
8 FTL 16.3 0
9 UBA52 16.3 0
10 HLA-B 16.3 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.7
bar=donor   line=cohort median 		14.4 14.2 80.1%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 86.6%
3 IL1B 9.7
bar=donor   line=cohort median 		8.8 9.3 73.3%
4 CXCL8 12.2
bar=donor   line=cohort median 		12.2 11.4 74.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 8.6
bar=donor   line=cohort median 		6.1 6.1 99.5%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.7 14.7 26.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.7
bar=donor   line=cohort median 		14.3 14.3 5.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.5
bar=donor   line=cohort median 		10.6 10.4 69.0%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 75.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.8 10.9 31.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 76.2%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 54.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 79.7%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 87.6%
18 MT-ND1 15.7
bar=donor   line=cohort median 		15.3 15.2 92.7%
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