GSM8077637

Dataset: gse255685 • Sample: Z514 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 82.3%ile (↑ High)
22,380 Genes with score > 0 Group median: 22,381 • 53.8%ile (≈ Median)
0 Median expression score Group median: 0 • 51.4%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

44.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.72
bar=donor   line=cohort median 		2.02 98.8%
FOXO3 Insulin/IGF-1 Signaling 9.57
bar=donor   line=cohort median 		9.99 5.6%
CETP Lipid Metabolism 4.39
bar=donor   line=cohort median 		5.05 0.2%
SIRT6 Sirtuin Family 8.62
bar=donor   line=cohort median 		8.34 88.4%
SIRT1 Sirtuin Family 8.14
bar=donor   line=cohort median 		8.72 2.7%
SIRT3 Sirtuin Family 7.72
bar=donor   line=cohort median 		7.49 85.5%
IGF1R Insulin/IGF-1 Signaling 9.66
bar=donor   line=cohort median 		10.21 8.4%
KLOTHO Anti-aging 2.31
bar=donor   line=cohort median 		2.51 17.7%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 92.7%
IL6 Inflammation 1.41
bar=donor   line=cohort median 		1.16 86.9%
TERT Telomere Maintenance 1.47
bar=donor   line=cohort median 		1.51 41.8%
IRS2 Insulin/IGF-1 Signaling 9.62
bar=donor   line=cohort median 		9.81 31.0%
TP53 Tumor Suppression 8.79
bar=donor   line=cohort median 		8.92 36.4%
SHC1 Signal Transduction 9.11
bar=donor   line=cohort median 		9.35 2.7%
ACE Signal Transduction 4.77
bar=donor   line=cohort median 		4.64 64.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.9 0
2 B2M 17.4 0
3 EEF1A1 17.0 0
4 ACTB 17.0 0
5 HLA-C 16.9 0
6 MT-RNR1 16.7 0
7 MT-CO1 16.7 0
8 HLA-B 16.7 0
9 S100A9 16.5 0
10 FTL 16.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.9
bar=donor   line=cohort median 		14.4 14.2 89.1%
2 S100A9 16.5
bar=donor   line=cohort median 		15.8 15.5 95.5%
3 IL1B 8.9
bar=donor   line=cohort median 		8.8 9.3 32.4%
4 CXCL8 12.6
bar=donor   line=cohort median 		12.2 11.4 85.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 35.3%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.7 14.7 27.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.0
bar=donor   line=cohort median 		14.3 14.3 25.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.8
bar=donor   line=cohort median 		10.6 10.4 90.1%
9 CD3E 12.4
bar=donor   line=cohort median 		12.1 12.0 93.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.5
bar=donor   line=cohort median 		10.8 10.9 10.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.7
bar=donor   line=cohort median 		12.2 11.7 93.7%
12 GNLY 13.3
bar=donor   line=cohort median 		12.4 12.1 98.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.7
bar=donor   line=cohort median 		16.5 16.4 93.0%
17 MT-CO2 16.1
bar=donor   line=cohort median 		15.6 15.3 97.7%
18 MT-ND1 15.8
bar=donor   line=cohort median 		15.3 15.2 96.6%
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