GSM8077638

Dataset: gse255685 • Sample: Z516 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 62.9%ile (≈ Median)
22,406 Genes with score > 0 Group median: 22,381 • 80.3%ile (↑ High)
0 Median expression score Group median: 0 • 79.0%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

50.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.14
bar=donor   line=cohort median 		2.02 68.3%
FOXO3 Insulin/IGF-1 Signaling 9.89
bar=donor   line=cohort median 		9.99 36.0%
CETP Lipid Metabolism 4.85
bar=donor   line=cohort median 		5.05 27.1%
SIRT6 Sirtuin Family 8.56
bar=donor   line=cohort median 		8.34 83.3%
SIRT1 Sirtuin Family 8.30
bar=donor   line=cohort median 		8.72 6.3%
SIRT3 Sirtuin Family 7.61
bar=donor   line=cohort median 		7.49 70.4%
IGF1R Insulin/IGF-1 Signaling 10.01
bar=donor   line=cohort median 		10.21 31.7%
KLOTHO Anti-aging 2.14
bar=donor   line=cohort median 		2.51 3.8%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 84.4%
IL6 Inflammation 1.13
bar=donor   line=cohort median 		1.16 41.8%
TERT Telomere Maintenance 1.52
bar=donor   line=cohort median 		1.51 52.9%
IRS2 Insulin/IGF-1 Signaling 10.74
bar=donor   line=cohort median 		9.81 91.6%
TP53 Tumor Suppression 8.63
bar=donor   line=cohort median 		8.92 17.4%
SHC1 Signal Transduction 9.31
bar=donor   line=cohort median 		9.35 38.5%
ACE Signal Transduction 5.41
bar=donor   line=cohort median 		4.64 98.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.3 0
3 EEF1A1 16.9 0
4 ACTB 16.8 0
5 HLA-B 16.6 0
6 HLA-C 16.6 0
7 MT-CO1 16.5 0
8 MT-RNR1 16.2 0
9 FTL 16.2 0
10 HLA-E 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.4 14.2 66.8%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 83.7%
3 IL1B 9.3
bar=donor   line=cohort median 		8.8 9.3 47.5%
4 CXCL8 13.1
bar=donor   line=cohort median 		12.2 11.4 93.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 36.7%
6 FCGR3B 14.0
bar=donor   line=cohort median 		14.7 14.7 9.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.6
bar=donor   line=cohort median 		14.3 14.3 4.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.0
bar=donor   line=cohort median 		10.6 10.4 93.4%
9 CD3E 12.4
bar=donor   line=cohort median 		12.1 12.0 94.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 41.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.7
bar=donor   line=cohort median 		12.2 11.7 93.4%
12 GNLY 12.4
bar=donor   line=cohort median 		12.4 12.1 74.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 66.1%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 91.2%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 86.6%
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