GSM8077639

Dataset: gse255685 • Sample: Z518 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 98.4%ile (↑ High)
22,368 Genes with score > 0 Group median: 22,381 • 35.7%ile (≈ Median)
0 Median expression score Group median: 0 • 76.9%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

53.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.07
bar=donor   line=cohort median 		2.02 59.0%
FOXO3 Insulin/IGF-1 Signaling 10.29
bar=donor   line=cohort median 		9.99 90.1%
CETP Lipid Metabolism 4.76
bar=donor   line=cohort median 		5.05 17.4%
SIRT6 Sirtuin Family 8.70
bar=donor   line=cohort median 		8.34 91.6%
SIRT1 Sirtuin Family 8.45
bar=donor   line=cohort median 		8.72 15.6%
SIRT3 Sirtuin Family 7.61
bar=donor   line=cohort median 		7.49 71.9%
IGF1R Insulin/IGF-1 Signaling 10.65
bar=donor   line=cohort median 		10.21 91.6%
KLOTHO Anti-aging 2.44
bar=donor   line=cohort median 		2.51 41.4%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 88.0%
IL6 Inflammation 1.14
bar=donor   line=cohort median 		1.16 44.3%
TERT Telomere Maintenance 1.43
bar=donor   line=cohort median 		1.51 31.4%
IRS2 Insulin/IGF-1 Signaling 10.64
bar=donor   line=cohort median 		9.81 88.4%
TP53 Tumor Suppression 8.27
bar=donor   line=cohort median 		8.92 0.9%
SHC1 Signal Transduction 9.34
bar=donor   line=cohort median 		9.35 45.0%
ACE Signal Transduction 4.46
bar=donor   line=cohort median 		4.64 32.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 CD177 65.5 0
2 MT-RNR2 18.0 0
3 B2M 17.6 0
4 S100A9 17.4 0
5 ACTB 17.3 0
6 EEF1A1 17.0 0
7 HLA-C 17.0 0
8 HLA-B 16.7 0
9 MT-RNR1 16.5 0
10 FTL 16.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 16.0
bar=donor   line=cohort median 		14.4 14.2 99.5%
2 S100A9 17.4
bar=donor   line=cohort median 		15.8 15.5 99.5%
3 IL1B 10.3
bar=donor   line=cohort median 		8.8 9.3 95.2%
4 CXCL8 13.6
bar=donor   line=cohort median 		12.2 11.4 97.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 40.7%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.7 14.7 54.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.3 14.3 57.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 77.2%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 80.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 7.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 73.7%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 57.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 54.7%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 91.6%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.3 15.2 80.8%
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