GSM8077641

Dataset: gse255685 • Sample: Z521 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 63.3%ile (≈ Median)
22,369 Genes with score > 0 Group median: 22,381 • 37.1%ile (≈ Median)
0 Median expression score Group median: 0 • 40.0%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

47.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.29
bar=donor   line=cohort median 		2.02 81.5%
FOXO3 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.99 63.6%
CETP Lipid Metabolism 4.86
bar=donor   line=cohort median 		5.05 29.6%
SIRT6 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.34 93.0%
SIRT1 Sirtuin Family 8.27
bar=donor   line=cohort median 		8.72 4.8%
SIRT3 Sirtuin Family 7.51
bar=donor   line=cohort median 		7.49 54.7%
IGF1R Insulin/IGF-1 Signaling 9.71
bar=donor   line=cohort median 		10.21 10.6%
KLOTHO Anti-aging 2.42
bar=donor   line=cohort median 		2.51 37.1%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 82.6%
IL6 Inflammation 1.02
bar=donor   line=cohort median 		1.16 16.0%
TERT Telomere Maintenance 1.31
bar=donor   line=cohort median 		1.51 9.1%
IRS2 Insulin/IGF-1 Signaling 10.96
bar=donor   line=cohort median 		9.81 96.6%
TP53 Tumor Suppression 8.66
bar=donor   line=cohort median 		8.92 21.7%
SHC1 Signal Transduction 9.27
bar=donor   line=cohort median 		9.35 23.8%
ACE Signal Transduction 5.13
bar=donor   line=cohort median 		4.64 91.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.0 0
2 B2M 17.4 0
3 EEF1A1 17.3 0
4 ACTB 16.8 0
5 MT-CO1 16.8 0
6 MT-RNR1 16.6 0
7 HLA-C 16.4 0
8 HLA-B 16.4 0
9 FTL 16.4 0
10 HLA-E 16.2 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.4 14.2 67.9%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 86.9%
3 IL1B 8.4
bar=donor   line=cohort median 		8.8 9.3 14.9%
4 CXCL8 11.8
bar=donor   line=cohort median 		12.2 11.4 63.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.9
bar=donor   line=cohort median 		6.1 6.1 85.5%
6 FCGR3B 15.2
bar=donor   line=cohort median 		14.7 14.7 83.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.2
bar=donor   line=cohort median 		14.3 14.3 37.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.0
bar=donor   line=cohort median 		10.6 10.4 96.2%
9 CD3E 12.5
bar=donor   line=cohort median 		12.1 12.0 95.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.3
bar=donor   line=cohort median 		10.8 10.9 4.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.7
bar=donor   line=cohort median 		12.2 11.7 94.1%
12 GNLY 13.1
bar=donor   line=cohort median 		12.4 12.1 93.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.8
bar=donor   line=cohort median 		16.5 16.4 96.2%
17 MT-CO2 16.0
bar=donor   line=cohort median 		15.6 15.3 96.2%
18 MT-ND1 15.8
bar=donor   line=cohort median 		15.3 15.2 95.5%
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