GSM8077642

Dataset: gse255685 • Sample: Z523 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 93.4%ile (↑ High)
22,412 Genes with score > 0 Group median: 22,381 • 86.4%ile (↑ High)
0 Median expression score Group median: 0 • 85.8%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

40.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.49
bar=donor   line=cohort median 		2.02 92.7%
FOXO3 Insulin/IGF-1 Signaling 9.55
bar=donor   line=cohort median 		9.99 4.1%
CETP Lipid Metabolism 4.69
bar=donor   line=cohort median 		5.05 10.9%
SIRT6 Sirtuin Family 9.04
bar=donor   line=cohort median 		8.34 99.5%
SIRT1 Sirtuin Family 7.98
bar=donor   line=cohort median 		8.72 0.9%
SIRT3 Sirtuin Family 7.73
bar=donor   line=cohort median 		7.49 89.4%
IGF1R Insulin/IGF-1 Signaling 9.30
bar=donor   line=cohort median 		10.21 0.9%
KLOTHO Anti-aging 2.37
bar=donor   line=cohort median 		2.51 29.9%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 90.1%
IL6 Inflammation 1.26
bar=donor   line=cohort median 		1.16 69.4%
TERT Telomere Maintenance 1.44
bar=donor   line=cohort median 		1.51 35.3%
IRS2 Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		9.81 41.4%
TP53 Tumor Suppression 8.53
bar=donor   line=cohort median 		8.92 12.0%
SHC1 Signal Transduction 9.12
bar=donor   line=cohort median 		9.35 3.4%
ACE Signal Transduction 4.47
bar=donor   line=cohort median 		4.64 33.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.4 0
3 HLA-C 17.0 0
4 ACTB 17.0 0
5 EEF1A1 16.9 0
6 HLA-B 16.8 0
7 MT-CO1 16.6 0
8 MT-RNR1 16.5 0
9 S100A9 16.5 0
10 FTL 16.3 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.9
bar=donor   line=cohort median 		14.4 14.2 89.4%
2 S100A9 16.5
bar=donor   line=cohort median 		15.8 15.5 95.2%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 31.0%
4 CXCL8 11.9
bar=donor   line=cohort median 		12.2 11.4 64.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.9
bar=donor   line=cohort median 		6.1 6.1 86.6%
6 FCGR3B 13.7
bar=donor   line=cohort median 		14.7 14.7 3.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.7
bar=donor   line=cohort median 		14.3 14.3 8.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.2
bar=donor   line=cohort median 		10.6 10.4 98.0%
9 CD3E 12.6
bar=donor   line=cohort median 		12.1 12.0 97.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.7
bar=donor   line=cohort median 		10.8 10.9 27.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 13.0
bar=donor   line=cohort median 		12.2 11.7 97.3%
12 GNLY 13.1
bar=donor   line=cohort median 		12.4 12.1 93.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 82.6%
17 MT-CO2 15.9
bar=donor   line=cohort median 		15.6 15.3 94.8%
18 MT-ND1 15.7
bar=donor   line=cohort median 		15.3 15.2 93.0%
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