GSM8077643

Dataset: gse255685 • Sample: Z528 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 81.2%ile (↑ High)
22,421 Genes with score > 0 Group median: 22,381 • 89.4%ile (↑ High)
0 Median expression score Group median: 0 • 88.0%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.50
bar=donor   line=cohort median 		2.02 93.0%
FOXO3 Insulin/IGF-1 Signaling 9.48
bar=donor   line=cohort median 		9.99 2.0%
CETP Lipid Metabolism 4.56
bar=donor   line=cohort median 		5.05 3.8%
SIRT6 Sirtuin Family 8.88
bar=donor   line=cohort median 		8.34 98.0%
SIRT1 Sirtuin Family 8.01
bar=donor   line=cohort median 		8.72 2.0%
SIRT3 Sirtuin Family 7.88
bar=donor   line=cohort median 		7.49 98.8%
IGF1R Insulin/IGF-1 Signaling 9.33
bar=donor   line=cohort median 		10.21 1.3%
KLOTHO Anti-aging 2.47
bar=donor   line=cohort median 		2.51 46.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 76.5%
IL6 Inflammation 1.30
bar=donor   line=cohort median 		1.16 76.5%
TERT Telomere Maintenance 1.30
bar=donor   line=cohort median 		1.51 8.1%
IRS2 Insulin/IGF-1 Signaling 9.82
bar=donor   line=cohort median 		9.81 50.7%
TP53 Tumor Suppression 8.67
bar=donor   line=cohort median 		8.92 22.8%
SHC1 Signal Transduction 9.23
bar=donor   line=cohort median 		9.35 11.3%
ACE Signal Transduction 4.39
bar=donor   line=cohort median 		4.64 26.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.2 0
3 EEF1A1 17.1 0
4 MT-CO1 16.9 0
5 HLA-C 16.9 0
6 ACTB 16.8 0
7 HLA-B 16.5 0
8 MT-RNR1 16.4 0
9 S100A9 16.2 0
10 MT-CO2 16.2 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.6
bar=donor   line=cohort median 		14.4 14.2 76.2%
2 S100A9 16.2
bar=donor   line=cohort median 		15.8 15.5 89.8%
3 IL1B 8.5
bar=donor   line=cohort median 		8.8 9.3 16.7%
4 CXCL8 11.7
bar=donor   line=cohort median 		12.2 11.4 59.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.5
bar=donor   line=cohort median 		6.1 6.1 72.6%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 47.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.0
bar=donor   line=cohort median 		14.3 14.3 21.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.5
bar=donor   line=cohort median 		10.6 10.4 99.8%
9 CD3E 12.6
bar=donor   line=cohort median 		12.1 12.0 98.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.3
bar=donor   line=cohort median 		10.8 10.9 5.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 13.6
bar=donor   line=cohort median 		12.2 11.7 99.5%
12 GNLY 13.4
bar=donor   line=cohort median 		12.4 12.1 98.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.9
bar=donor   line=cohort median 		16.5 16.4 98.0%
17 MT-CO2 16.2
bar=donor   line=cohort median 		15.6 15.3 98.4%
18 MT-ND1 15.7
bar=donor   line=cohort median 		15.3 15.2 94.1%
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