GSM8077644

Dataset: gse255685 • Sample: Z531 • Status: Healthy control
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 30.6%ile (≈ Median)
22,349 Genes with score > 0 Group median: 22,381 • 13.6%ile (↓ Low)
0 Median expression score Group median: 0 • 22.0%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

53.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.69
bar=donor   line=cohort median 		2.02 1.3%
FOXO3 Insulin/IGF-1 Signaling 10.27
bar=donor   line=cohort median 		9.99 88.0%
CETP Lipid Metabolism 5.19
bar=donor   line=cohort median 		5.05 70.4%
SIRT6 Sirtuin Family 8.34
bar=donor   line=cohort median 		8.34 51.4%
SIRT1 Sirtuin Family 9.00
bar=donor   line=cohort median 		8.72 94.4%
SIRT3 Sirtuin Family 7.37
bar=donor   line=cohort median 		7.49 28.9%
IGF1R Insulin/IGF-1 Signaling 10.31
bar=donor   line=cohort median 		10.21 59.0%
KLOTHO Anti-aging 2.73
bar=donor   line=cohort median 		2.51 79.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 24.6%
IL6 Inflammation 1.15
bar=donor   line=cohort median 		1.16 48.2%
TERT Telomere Maintenance 1.27
bar=donor   line=cohort median 		1.51 1.6%
IRS2 Insulin/IGF-1 Signaling 9.78
bar=donor   line=cohort median 		9.81 46.4%
TP53 Tumor Suppression 9.01
bar=donor   line=cohort median 		8.92 66.1%
SHC1 Signal Transduction 9.34
bar=donor   line=cohort median 		9.35 45.3%
ACE Signal Transduction 5.21
bar=donor   line=cohort median 		4.64 93.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 17.0 0
3 EEF1A1 16.7 0
4 MT-CO1 16.5 0
5 ACTB 16.5 0
6 HLA-C 16.3 0
7 HLA-B 16.0 0
8 MT-RNR1 15.8 0
9 HLA-E 15.8 0
10 MT-ND4 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.0
bar=donor   line=cohort median 		14.4 14.2 38.9%
2 S100A9 15.5
bar=donor   line=cohort median 		15.8 15.5 49.6%
3 IL1B 9.8
bar=donor   line=cohort median 		8.8 9.3 76.2%
4 CXCL8 11.4
bar=donor   line=cohort median 		12.2 11.4 49.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.2
bar=donor   line=cohort median 		6.1 6.1 60.0%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 72.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.3 14.3 58.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.6 10.4 49.3%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 32.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 46.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.7
bar=donor   line=cohort median 		12.2 11.7 52.2%
12 GNLY 11.6
bar=donor   line=cohort median 		12.4 12.1 16.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 74.4%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 48.2%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 47.5%
◂ Previous Donor Back to Donor List Next Donor ▸