GSM8077645

Dataset: gse255685 • Sample: Z559 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 91.2%ile (↑ High)
22,378 Genes with score > 0 Group median: 22,381 • 50.0%ile (≈ Median)
0 Median expression score Group median: 0 • 24.9%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

44.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.57
bar=donor   line=cohort median 		2.02 95.5%
FOXO3 Insulin/IGF-1 Signaling 9.94
bar=donor   line=cohort median 		9.99 43.6%
CETP Lipid Metabolism 4.80
bar=donor   line=cohort median 		5.05 20.3%
SIRT6 Sirtuin Family 8.61
bar=donor   line=cohort median 		8.34 87.6%
SIRT1 Sirtuin Family 7.91
bar=donor   line=cohort median 		8.72 0.5%
SIRT3 Sirtuin Family 7.61
bar=donor   line=cohort median 		7.49 71.5%
IGF1R Insulin/IGF-1 Signaling 9.29
bar=donor   line=cohort median 		10.21 0.2%
KLOTHO Anti-aging 2.42
bar=donor   line=cohort median 		2.51 36.4%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 92.3%
IL6 Inflammation 1.05
bar=donor   line=cohort median 		1.16 18.8%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 66.5%
IRS2 Insulin/IGF-1 Signaling 10.27
bar=donor   line=cohort median 		9.81 76.5%
TP53 Tumor Suppression 8.44
bar=donor   line=cohort median 		8.92 4.8%
SHC1 Signal Transduction 8.87
bar=donor   line=cohort median 		9.35 0.2%
ACE Signal Transduction 4.73
bar=donor   line=cohort median 		4.64 59.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.9 0
2 B2M 17.4 0
3 ACTB 17.2 0
4 EEF1A1 17.2 0
5 HLA-B 17.0 0
6 MT-CO1 16.7 0
7 MT-RNR1 16.6 0
8 FTL 16.6 0
9 S100A9 16.6 0
10 UBA52 16.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.9
bar=donor   line=cohort median 		14.4 14.2 89.8%
2 S100A9 16.6
bar=donor   line=cohort median 		15.8 15.5 97.0%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 28.5%
4 CXCL8 12.8
bar=donor   line=cohort median 		12.2 11.4 89.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.7
bar=donor   line=cohort median 		6.1 6.1 80.8%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 45.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 31.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.3
bar=donor   line=cohort median 		10.6 10.4 98.4%
9 CD3E 12.9
bar=donor   line=cohort median 		12.1 12.0 99.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.2
bar=donor   line=cohort median 		10.8 10.9 2.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 13.7
bar=donor   line=cohort median 		12.2 11.7 99.8%
12 GNLY 14.3
bar=donor   line=cohort median 		12.4 12.1 99.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.7
bar=donor   line=cohort median 		16.5 16.4 93.4%
17 MT-CO2 16.3
bar=donor   line=cohort median 		15.6 15.3 99.1%
18 MT-ND1 15.9
bar=donor   line=cohort median 		15.3 15.2 97.0%
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