GSM8077646

Dataset: gse255685 • Sample: Z560 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 57.9%ile (≈ Median)
22,403 Genes with score > 0 Group median: 22,381 • 75.6%ile (↑ High)
0 Median expression score Group median: 0 • 76.5%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.30
bar=donor   line=cohort median 		2.02 83.0%
FOXO3 Insulin/IGF-1 Signaling 9.84
bar=donor   line=cohort median 		9.99 27.8%
CETP Lipid Metabolism 4.60
bar=donor   line=cohort median 		5.05 5.9%
SIRT6 Sirtuin Family 8.67
bar=donor   line=cohort median 		8.34 90.5%
SIRT1 Sirtuin Family 8.19
bar=donor   line=cohort median 		8.72 4.5%
SIRT3 Sirtuin Family 7.63
bar=donor   line=cohort median 		7.49 75.5%
IGF1R Insulin/IGF-1 Signaling 9.57
bar=donor   line=cohort median 		10.21 6.6%
KLOTHO Anti-aging 2.18
bar=donor   line=cohort median 		2.51 6.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 53.9%
IL6 Inflammation 1.54
bar=donor   line=cohort median 		1.16 93.7%
TERT Telomere Maintenance 1.46
bar=donor   line=cohort median 		1.51 41.0%
IRS2 Insulin/IGF-1 Signaling 9.96
bar=donor   line=cohort median 		9.81 61.5%
TP53 Tumor Suppression 8.38
bar=donor   line=cohort median 		8.92 2.7%
SHC1 Signal Transduction 9.18
bar=donor   line=cohort median 		9.35 7.4%
ACE Signal Transduction 4.83
bar=donor   line=cohort median 		4.64 68.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.0 0
2 B2M 17.4 0
3 EEF1A1 17.2 0
4 MT-CO1 16.9 0
5 ACTB 16.9 0
6 HLA-C 16.8 0
7 MT-RNR1 16.7 0
8 HLA-B 16.7 0
9 MT-CO3 16.2 0
10 HLA-E 16.2 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.6
bar=donor   line=cohort median 		14.4 14.2 74.7%
2 S100A9 16.2
bar=donor   line=cohort median 		15.8 15.5 89.1%
3 IL1B 9.7
bar=donor   line=cohort median 		8.8 9.3 70.8%
4 CXCL8 13.7
bar=donor   line=cohort median 		12.2 11.4 97.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 36.4%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 45.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.3
bar=donor   line=cohort median 		14.3 14.3 50.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.0
bar=donor   line=cohort median 		10.6 10.4 95.5%
9 CD3E 12.5
bar=donor   line=cohort median 		12.1 12.0 97.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.5
bar=donor   line=cohort median 		10.8 10.9 12.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 13.2
bar=donor   line=cohort median 		12.2 11.7 98.0%
12 GNLY 13.8
bar=donor   line=cohort median 		12.4 12.1 98.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.9
bar=donor   line=cohort median 		16.5 16.4 98.4%
17 MT-CO2 16.0
bar=donor   line=cohort median 		15.6 15.3 96.6%
18 MT-ND1 15.9
bar=donor   line=cohort median 		15.3 15.2 97.3%
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