GSM8077647

Dataset: gse255685 • Sample: Z561 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 76.2%ile (↑ High)
22,405 Genes with score > 0 Group median: 22,381 • 78.3%ile (↑ High)
0 Median expression score Group median: 0 • 65.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.77
bar=donor   line=cohort median 		2.02 99.5%
FOXO3 Insulin/IGF-1 Signaling 9.81
bar=donor   line=cohort median 		9.99 25.3%
CETP Lipid Metabolism 5.19
bar=donor   line=cohort median 		5.05 71.2%
SIRT6 Sirtuin Family 8.98
bar=donor   line=cohort median 		8.34 98.8%
SIRT1 Sirtuin Family 7.89
bar=donor   line=cohort median 		8.72 0.2%
SIRT3 Sirtuin Family 7.65
bar=donor   line=cohort median 		7.49 77.6%
IGF1R Insulin/IGF-1 Signaling 9.97
bar=donor   line=cohort median 		10.21 29.9%
KLOTHO Anti-aging 2.14
bar=donor   line=cohort median 		2.51 3.4%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 84.1%
IL6 Inflammation 1.33
bar=donor   line=cohort median 		1.16 82.3%
TERT Telomere Maintenance 1.31
bar=donor   line=cohort median 		1.51 9.9%
IRS2 Insulin/IGF-1 Signaling 9.92
bar=donor   line=cohort median 		9.81 59.7%
TP53 Tumor Suppression 8.65
bar=donor   line=cohort median 		8.92 20.6%
SHC1 Signal Transduction 9.15
bar=donor   line=cohort median 		9.35 4.8%
ACE Signal Transduction 4.38
bar=donor   line=cohort median 		4.64 24.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 B2M 17.3 0
2 MT-RNR2 17.1 0
3 ACTB 17.0 0
4 EEF1A1 16.9 0
5 S100A9 16.7 0
6 HLA-B 16.6 0
7 FTL 16.3 0
8 HLA-C 16.2 0
9 HLA-E 16.2 0
10 TMSB4X 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.0
bar=donor   line=cohort median 		14.4 14.2 92.7%
2 S100A9 16.7
bar=donor   line=cohort median 		15.8 15.5 98.0%
3 IL1B 9.1
bar=donor   line=cohort median 		8.8 9.3 41.0%
4 CXCL8 13.0
bar=donor   line=cohort median 		12.2 11.4 92.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 8.2
bar=donor   line=cohort median 		6.1 6.1 98.4%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.7 14.7 58.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 72.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 75.8%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 53.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.3
bar=donor   line=cohort median 		10.8 10.9 3.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.2
bar=donor   line=cohort median 		12.2 11.7 81.5%
12 GNLY 12.1
bar=donor   line=cohort median 		12.4 12.1 51.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.0
bar=donor   line=cohort median 		16.5 16.4 0.9%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 41.4%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 59.7%
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