GSM8077648

Dataset: gse255685 • Sample: Z565 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 5.9%ile (↓ Low)
22,357 Genes with score > 0 Group median: 22,381 • 23.1%ile (↓ Low)
0 Median expression score Group median: 0 • 24.2%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

40.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.37
bar=donor   line=cohort median 		2.02 86.9%
FOXO3 Insulin/IGF-1 Signaling 9.56
bar=donor   line=cohort median 		9.99 4.8%
CETP Lipid Metabolism 4.62
bar=donor   line=cohort median 		5.05 6.6%
SIRT6 Sirtuin Family 8.50
bar=donor   line=cohort median 		8.34 76.9%
SIRT1 Sirtuin Family 8.60
bar=donor   line=cohort median 		8.72 33.9%
SIRT3 Sirtuin Family 7.74
bar=donor   line=cohort median 		7.49 89.8%
IGF1R Insulin/IGF-1 Signaling 9.92
bar=donor   line=cohort median 		10.21 26.0%
KLOTHO Anti-aging 2.27
bar=donor   line=cohort median 		2.51 13.8%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 57.5%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 10.6%
TERT Telomere Maintenance 1.55
bar=donor   line=cohort median 		1.51 57.2%
IRS2 Insulin/IGF-1 Signaling 9.53
bar=donor   line=cohort median 		9.81 23.5%
TP53 Tumor Suppression 8.97
bar=donor   line=cohort median 		8.92 58.6%
SHC1 Signal Transduction 9.34
bar=donor   line=cohort median 		9.35 46.8%
ACE Signal Transduction 4.25
bar=donor   line=cohort median 		4.64 12.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.1 0
3 EEF1A1 16.9 0
4 ACTB 16.8 0
5 MT-CO1 16.7 0
6 HLA-C 16.5 0
7 HLA-B 16.3 0
8 MT-RNR1 16.0 0
9 FTL 16.0 0
10 HLA-E 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.1
bar=donor   line=cohort median 		14.4 14.2 45.3%
2 S100A9 15.8
bar=donor   line=cohort median 		15.8 15.5 69.0%
3 IL1B 9.7
bar=donor   line=cohort median 		8.8 9.3 72.9%
4 CXCL8 11.1
bar=donor   line=cohort median 		12.2 11.4 43.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 28.5%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 44.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.8
bar=donor   line=cohort median 		14.3 14.3 10.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.5
bar=donor   line=cohort median 		10.6 10.4 64.0%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 83.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 43.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.7
bar=donor   line=cohort median 		12.2 11.7 92.3%
12 GNLY 13.2
bar=donor   line=cohort median 		12.4 12.1 95.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.7
bar=donor   line=cohort median 		16.5 16.4 91.2%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 86.6%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 47.8%
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