GSM8077650

Dataset: gse255685 • Sample: Z570 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 51.4%ile (≈ Median)
22,376 Genes with score > 0 Group median: 22,381 • 46.8%ile (≈ Median)
0 Median expression score Group median: 0 • 61.8%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

49.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.41
bar=donor   line=cohort median 		2.02 88.4%
FOXO3 Insulin/IGF-1 Signaling 10.16
bar=donor   line=cohort median 		9.99 77.6%
CETP Lipid Metabolism 4.67
bar=donor   line=cohort median 		5.05 9.5%
SIRT6 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.34 93.4%
SIRT1 Sirtuin Family 8.43
bar=donor   line=cohort median 		8.72 13.8%
SIRT3 Sirtuin Family 7.41
bar=donor   line=cohort median 		7.49 35.3%
IGF1R Insulin/IGF-1 Signaling 10.33
bar=donor   line=cohort median 		10.21 62.2%
KLOTHO Anti-aging 2.71
bar=donor   line=cohort median 		2.51 76.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 67.9%
IL6 Inflammation 1.11
bar=donor   line=cohort median 		1.16 35.7%
TERT Telomere Maintenance 1.30
bar=donor   line=cohort median 		1.51 7.0%
IRS2 Insulin/IGF-1 Signaling 10.57
bar=donor   line=cohort median 		9.81 85.8%
TP53 Tumor Suppression 8.50
bar=donor   line=cohort median 		8.92 9.5%
SHC1 Signal Transduction 9.46
bar=donor   line=cohort median 		9.35 79.4%
ACE Signal Transduction 4.01
bar=donor   line=cohort median 		4.64 2.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.5 0
3 ACTB 17.1 0
4 HLA-C 17.0 0
5 EEF1A1 16.9 0
6 S100A9 16.6 0
7 HLA-B 16.5 0
8 MT-CO1 16.4 0
9 HLA-E 16.4 0
10 FTL 16.3 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.1
bar=donor   line=cohort median 		14.4 14.2 95.2%
2 S100A9 16.6
bar=donor   line=cohort median 		15.8 15.5 96.2%
3 IL1B 9.9
bar=donor   line=cohort median 		8.8 9.3 83.3%
4 CXCL8 14.5
bar=donor   line=cohort median 		12.2 11.4 99.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 23.8%
6 FCGR3B 15.1
bar=donor   line=cohort median 		14.7 14.7 76.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 73.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 33.9%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 45.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.6
bar=donor   line=cohort median 		10.8 10.9 19.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.3
bar=donor   line=cohort median 		12.2 11.7 83.7%
12 GNLY 12.7
bar=donor   line=cohort median 		12.4 12.1 82.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 52.5%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 90.5%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 87.3%
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