GSM8077652

Dataset: gse255685 • Sample: Z572 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 99.8%ile (↑ High)
22,484 Genes with score > 0 Group median: 22,381 • 99.5%ile (↑ High)
0 Median expression score Group median: 0 • 99.8%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.64
bar=donor   line=cohort median 		2.02 96.6%
FOXO3 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.99 65.1%
CETP Lipid Metabolism 4.88
bar=donor   line=cohort median 		5.05 31.7%
SIRT6 Sirtuin Family 8.71
bar=donor   line=cohort median 		8.34 92.3%
SIRT1 Sirtuin Family 8.27
bar=donor   line=cohort median 		8.72 5.2%
SIRT3 Sirtuin Family 7.36
bar=donor   line=cohort median 		7.49 27.8%
IGF1R Insulin/IGF-1 Signaling 10.29
bar=donor   line=cohort median 		10.21 57.9%
KLOTHO Anti-aging 2.32
bar=donor   line=cohort median 		2.51 21.7%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 80.5%
IL6 Inflammation 1.32
bar=donor   line=cohort median 		1.16 79.8%
TERT Telomere Maintenance 1.51
bar=donor   line=cohort median 		1.51 50.0%
IRS2 Insulin/IGF-1 Signaling 10.50
bar=donor   line=cohort median 		9.81 84.4%
TP53 Tumor Suppression 8.25
bar=donor   line=cohort median 		8.92 0.5%
SHC1 Signal Transduction 9.00
bar=donor   line=cohort median 		9.35 0.5%
ACE Signal Transduction 4.86
bar=donor   line=cohort median 		4.64 73.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 CD177 20.1 0
2 MT-RNR2 17.8 0
3 S100A9 17.5 0
4 B2M 17.2 0
5 MT-CO1 17.1 0
6 ACTB 16.9 0
7 EEF1A1 16.5 0
8 HLA-B 16.4 0
9 MT-RNR1 16.3 0
10 HLA-C 16.3 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 16.0
bar=donor   line=cohort median 		14.4 14.2 99.8%
2 S100A9 17.5
bar=donor   line=cohort median 		15.8 15.5 99.8%
3 IL1B 10.0
bar=donor   line=cohort median 		8.8 9.3 86.2%
4 CXCL8 13.4
bar=donor   line=cohort median 		12.2 11.4 95.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 56.1%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.7 14.7 60.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.4
bar=donor   line=cohort median 		14.3 14.3 2.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.1
bar=donor   line=cohort median 		10.6 10.4 96.6%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 29.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.7
bar=donor   line=cohort median 		10.8 10.9 26.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.2
bar=donor   line=cohort median 		12.2 11.7 78.7%
12 GNLY 12.8
bar=donor   line=cohort median 		12.4 12.1 87.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 17.1
bar=donor   line=cohort median 		16.5 16.4 99.5%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 89.1%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 64.0%
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