GSM8077653

Dataset: gse255685 • Sample: Z575 • Status: Healthy control
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 97.3%ile (↑ High)
22,404 Genes with score > 0 Group median: 22,381 • 76.5%ile (↑ High)
0 Median expression score Group median: 0 • 64.7%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

59.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.06
bar=donor   line=cohort median 		2.02 58.2%
FOXO3 Insulin/IGF-1 Signaling 10.63
bar=donor   line=cohort median 		9.99 99.1%
CETP Lipid Metabolism 4.87
bar=donor   line=cohort median 		5.05 29.9%
SIRT6 Sirtuin Family 8.48
bar=donor   line=cohort median 		8.34 73.7%
SIRT1 Sirtuin Family 8.82
bar=donor   line=cohort median 		8.72 71.9%
SIRT3 Sirtuin Family 7.34
bar=donor   line=cohort median 		7.49 24.2%
IGF1R Insulin/IGF-1 Signaling 10.75
bar=donor   line=cohort median 		10.21 96.6%
KLOTHO Anti-aging 2.52
bar=donor   line=cohort median 		2.51 51.8%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 86.9%
IL6 Inflammation 1.14
bar=donor   line=cohort median 		1.16 43.2%
TERT Telomere Maintenance 1.53
bar=donor   line=cohort median 		1.51 53.6%
IRS2 Insulin/IGF-1 Signaling 11.20
bar=donor   line=cohort median 		9.81 97.7%
TP53 Tumor Suppression 8.30
bar=donor   line=cohort median 		8.92 1.3%
SHC1 Signal Transduction 9.54
bar=donor   line=cohort median 		9.35 91.2%
ACE Signal Transduction 4.30
bar=donor   line=cohort median 		4.64 16.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 17.2 0
3 ACTB 16.9 0
4 EEF1A1 16.8 0
5 HLA-C 16.6 0
6 MT-CO1 16.5 0
7 S100A9 16.4 0
8 CSF3R 16.1 0
9 HLA-E 16.1 0
10 FTL 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.0
bar=donor   line=cohort median 		14.4 14.2 93.0%
2 S100A9 16.4
bar=donor   line=cohort median 		15.8 15.5 93.4%
3 IL1B 10.4
bar=donor   line=cohort median 		8.8 9.3 95.9%
4 CXCL8 13.4
bar=donor   line=cohort median 		12.2 11.4 96.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.5
bar=donor   line=cohort median 		6.1 6.1 71.1%
6 FCGR3B 15.6
bar=donor   line=cohort median 		14.7 14.7 98.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.3 14.3 55.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.8
bar=donor   line=cohort median 		10.6 10.4 6.3%
9 CD3E 11.6
bar=donor   line=cohort median 		12.1 12.0 2.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 44.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 10.9
bar=donor   line=cohort median 		12.2 11.7 0.2%
12 GNLY 11.4
bar=donor   line=cohort median 		12.4 12.1 7.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 64.3%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 67.6%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 70.4%
◂ Previous Donor Back to Donor List Next Donor ▸