GSM8077654

Dataset: gse255685 • Sample: Z576 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 83.3%ile (↑ High)
22,381 Genes with score > 0 Group median: 22,381 • 55.9%ile (≈ Median)
0 Median expression score Group median: 0 • 74.0%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

56.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.25
bar=donor   line=cohort median 		2.02 80.1%
FOXO3 Insulin/IGF-1 Signaling 10.43
bar=donor   line=cohort median 		9.99 94.8%
CETP Lipid Metabolism 4.83
bar=donor   line=cohort median 		5.05 24.2%
SIRT6 Sirtuin Family 8.23
bar=donor   line=cohort median 		8.34 25.6%
SIRT1 Sirtuin Family 8.82
bar=donor   line=cohort median 		8.72 70.4%
SIRT3 Sirtuin Family 7.03
bar=donor   line=cohort median 		7.49 1.6%
IGF1R Insulin/IGF-1 Signaling 10.44
bar=donor   line=cohort median 		10.21 76.2%
KLOTHO Anti-aging 2.55
bar=donor   line=cohort median 		2.51 56.8%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 30.7%
IL6 Inflammation 1.49
bar=donor   line=cohort median 		1.16 93.0%
TERT Telomere Maintenance 1.82
bar=donor   line=cohort median 		1.51 91.2%
IRS2 Insulin/IGF-1 Signaling 10.54
bar=donor   line=cohort median 		9.81 85.1%
TP53 Tumor Suppression 8.67
bar=donor   line=cohort median 		8.92 23.8%
SHC1 Signal Transduction 9.51
bar=donor   line=cohort median 		9.35 88.0%
ACE Signal Transduction 4.20
bar=donor   line=cohort median 		4.64 8.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 17.0 0
3 EEF1A1 16.8 0
4 ACTB 16.5 0
5 MT-CO1 16.4 0
6 HLA-C 16.3 0
7 MT-RNR1 15.9 0
8 HLA-E 15.8 0
9 HLA-B 15.7 0
10 FTL 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.4 14.2 32.4%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 43.5%
3 IL1B 8.6
bar=donor   line=cohort median 		8.8 9.3 20.6%
4 CXCL8 12.9
bar=donor   line=cohort median 		12.2 11.4 91.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.4
bar=donor   line=cohort median 		6.1 6.1 68.3%
6 FCGR3B 15.1
bar=donor   line=cohort median 		14.7 14.7 81.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 89.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 28.9%
9 CD3E 11.7
bar=donor   line=cohort median 		12.1 12.0 13.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.8 10.9 61.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		12.2 11.7 44.3%
12 GNLY 11.8
bar=donor   line=cohort median 		12.4 12.1 26.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 33.9%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 42.8%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.3 15.2 30.3%
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