GSM8077655

Dataset: gse255685 • Sample: Z577 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 94.4%ile (↑ High)
22,433 Genes with score > 0 Group median: 22,381 • 94.1%ile (↑ High)
0 Median expression score Group median: 0 • 93.0%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

49.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.20
bar=donor   line=cohort median 		2.02 75.8%
FOXO3 Insulin/IGF-1 Signaling 10.29
bar=donor   line=cohort median 		9.99 90.5%
CETP Lipid Metabolism 4.59
bar=donor   line=cohort median 		5.05 4.8%
SIRT6 Sirtuin Family 8.36
bar=donor   line=cohort median 		8.34 57.2%
SIRT1 Sirtuin Family 8.60
bar=donor   line=cohort median 		8.72 34.2%
SIRT3 Sirtuin Family 7.43
bar=donor   line=cohort median 		7.49 38.2%
IGF1R Insulin/IGF-1 Signaling 10.32
bar=donor   line=cohort median 		10.21 60.4%
KLOTHO Anti-aging 2.66
bar=donor   line=cohort median 		2.51 70.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 32.1%
IL6 Inflammation 1.16
bar=donor   line=cohort median 		1.16 50.0%
TERT Telomere Maintenance 1.51
bar=donor   line=cohort median 		1.51 50.4%
IRS2 Insulin/IGF-1 Signaling 10.67
bar=donor   line=cohort median 		9.81 89.4%
TP53 Tumor Suppression 8.53
bar=donor   line=cohort median 		8.92 12.7%
SHC1 Signal Transduction 9.42
bar=donor   line=cohort median 		9.35 73.3%
ACE Signal Transduction 4.16
bar=donor   line=cohort median 		4.64 6.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 16.8 0
3 EEF1A1 16.8 0
4 ACTB 16.4 0
5 MT-CO1 16.4 0
6 HLA-C 16.2 0
7 MT-RNR1 16.0 0
8 HLA-B 15.7 0
9 HLA-E 15.7 0
10 FTL 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.8
bar=donor   line=cohort median 		14.4 14.2 29.6%
2 S100A9 15.3
bar=donor   line=cohort median 		15.8 15.5 34.2%
3 IL1B 9.3
bar=donor   line=cohort median 		8.8 9.3 47.8%
4 CXCL8 13.8
bar=donor   line=cohort median 		12.2 11.4 98.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 53.9%
6 FCGR3B 14.2
bar=donor   line=cohort median 		14.7 14.7 15.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.3 14.3 56.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.1
bar=donor   line=cohort median 		10.6 10.4 18.1%
9 CD3E 11.7
bar=donor   line=cohort median 		12.1 12.0 7.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 48.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		12.2 11.7 31.4%
12 GNLY 11.3
bar=donor   line=cohort median 		12.4 12.1 2.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 36.7%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 43.9%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.3 15.2 31.0%
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