GSM8077657

Dataset: gse255685 • Sample: Z581 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 88.0%ile (↑ High)
22,409 Genes with score > 0 Group median: 22,381 • 82.8%ile (↑ High)
0 Median expression score Group median: 0 • 91.9%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.09
bar=donor   line=cohort median 		2.02 62.2%
FOXO3 Insulin/IGF-1 Signaling 10.44
bar=donor   line=cohort median 		9.99 95.2%
CETP Lipid Metabolism 4.94
bar=donor   line=cohort median 		5.05 37.5%
SIRT6 Sirtuin Family 8.16
bar=donor   line=cohort median 		8.34 13.8%
SIRT1 Sirtuin Family 8.72
bar=donor   line=cohort median 		8.72 50.4%
SIRT3 Sirtuin Family 7.24
bar=donor   line=cohort median 		7.49 9.1%
IGF1R Insulin/IGF-1 Signaling 10.38
bar=donor   line=cohort median 		10.21 70.4%
KLOTHO Anti-aging 2.62
bar=donor   line=cohort median 		2.51 66.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 38.2%
IL6 Inflammation 1.17
bar=donor   line=cohort median 		1.16 51.4%
TERT Telomere Maintenance 1.52
bar=donor   line=cohort median 		1.51 52.2%
IRS2 Insulin/IGF-1 Signaling 10.57
bar=donor   line=cohort median 		9.81 86.2%
TP53 Tumor Suppression 8.51
bar=donor   line=cohort median 		8.92 10.2%
SHC1 Signal Transduction 9.43
bar=donor   line=cohort median 		9.35 75.1%
ACE Signal Transduction 4.59
bar=donor   line=cohort median 		4.64 46.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MTCO2P12 28.9 0
2 MT-RNR2 17.7 0
3 B2M 17.0 0
4 EEF1A1 16.8 0
5 MT-CO1 16.5 0
6 ACTB 16.5 0
7 HLA-C 16.3 0
8 MT-RNR1 16.2 0
9 HLA-E 15.8 0
10 HLA-B 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.4 14.2 32.1%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 45.0%
3 IL1B 8.7
bar=donor   line=cohort median 		8.8 9.3 23.5%
4 CXCL8 12.1
bar=donor   line=cohort median 		12.2 11.4 71.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 32.8%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 38.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 26.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 32.8%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 32.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.6
bar=donor   line=cohort median 		10.8 10.9 23.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.5
bar=donor   line=cohort median 		12.2 11.7 33.9%
12 GNLY 11.5
bar=donor   line=cohort median 		12.4 12.1 11.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 62.2%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.6 15.3 71.1%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.3 15.2 84.8%
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