GSM8077658

Dataset: gse255685 • Sample: Z582 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 97.7%ile (↑ High)
22,466 Genes with score > 0 Group median: 22,381 • 99.1%ile (↑ High)
0 Median expression score Group median: 0 • 99.5%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

53.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.24
bar=donor   line=cohort median 		2.02 79.8%
FOXO3 Insulin/IGF-1 Signaling 10.48
bar=donor   line=cohort median 		9.99 96.2%
CETP Lipid Metabolism 5.07
bar=donor   line=cohort median 		5.05 52.2%
SIRT6 Sirtuin Family 8.21
bar=donor   line=cohort median 		8.34 20.3%
SIRT1 Sirtuin Family 8.75
bar=donor   line=cohort median 		8.72 55.7%
SIRT3 Sirtuin Family 7.25
bar=donor   line=cohort median 		7.49 10.2%
IGF1R Insulin/IGF-1 Signaling 10.41
bar=donor   line=cohort median 		10.21 72.2%
KLOTHO Anti-aging 3.09
bar=donor   line=cohort median 		2.51 99.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 29.6%
IL6 Inflammation 1.23
bar=donor   line=cohort median 		1.16 64.0%
TERT Telomere Maintenance 1.36
bar=donor   line=cohort median 		1.51 15.2%
IRS2 Insulin/IGF-1 Signaling 11.25
bar=donor   line=cohort median 		9.81 98.4%
TP53 Tumor Suppression 8.49
bar=donor   line=cohort median 		8.92 6.6%
SHC1 Signal Transduction 9.42
bar=donor   line=cohort median 		9.35 70.4%
ACE Signal Transduction 4.46
bar=donor   line=cohort median 		4.64 31.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 16.9 0
3 EEF1A1 16.8 0
4 MT-CO1 16.4 0
5 ACTB 16.3 0
6 HLA-C 15.9 0
7 HLA-B 15.8 0
8 HLA-E 15.7 0
9 MT-RNR1 15.7 0
10 TXNIP 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.4
bar=donor   line=cohort median 		14.4 14.2 13.8%
2 S100A9 15.1
bar=donor   line=cohort median 		15.8 15.5 21.7%
3 IL1B 8.6
bar=donor   line=cohort median 		8.8 9.3 19.2%
4 CXCL8 12.8
bar=donor   line=cohort median 		12.2 11.4 90.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.1 6.1 45.0%
6 FCGR3B 13.7
bar=donor   line=cohort median 		14.7 14.7 3.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.8
bar=donor   line=cohort median 		14.3 14.3 84.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.1
bar=donor   line=cohort median 		10.6 10.4 23.1%
9 CD3E 11.7
bar=donor   line=cohort median 		12.1 12.0 9.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.8 10.9 36.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		12.2 11.7 45.3%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 58.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 36.0%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.6 15.3 24.9%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.3 15.2 28.9%
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