GSM8077659

Dataset: gse255685 • Sample: Z583 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 99.5%ile (↑ High)
22,421 Genes with score > 0 Group median: 22,381 • 89.4%ile (↑ High)
0 Median expression score Group median: 0 • 91.2%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

59.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.98
bar=donor   line=cohort median 		2.02 45.0%
FOXO3 Insulin/IGF-1 Signaling 10.50
bar=donor   line=cohort median 		9.99 97.0%
CETP Lipid Metabolism 4.61
bar=donor   line=cohort median 		5.05 6.3%
SIRT6 Sirtuin Family 8.52
bar=donor   line=cohort median 		8.34 79.4%
SIRT1 Sirtuin Family 8.68
bar=donor   line=cohort median 		8.72 45.3%
SIRT3 Sirtuin Family 7.28
bar=donor   line=cohort median 		7.49 14.2%
IGF1R Insulin/IGF-1 Signaling 10.61
bar=donor   line=cohort median 		10.21 89.4%
KLOTHO Anti-aging 2.67
bar=donor   line=cohort median 		2.51 71.2%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 18.1%
IL6 Inflammation 1.46
bar=donor   line=cohort median 		1.16 90.9%
TERT Telomere Maintenance 1.84
bar=donor   line=cohort median 		1.51 93.4%
IRS2 Insulin/IGF-1 Signaling 11.24
bar=donor   line=cohort median 		9.81 98.0%
TP53 Tumor Suppression 8.64
bar=donor   line=cohort median 		8.92 19.2%
SHC1 Signal Transduction 9.45
bar=donor   line=cohort median 		9.35 78.7%
ACE Signal Transduction 4.57
bar=donor   line=cohort median 		4.64 43.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 IGLV3-19 68.1 0
2 MT-RNR2 17.4 0
3 B2M 17.2 0
4 ACTB 16.7 0
5 EEF1A1 16.6 0
6 MT-CO1 16.4 0
7 HLA-C 16.2 0
8 HLA-B 16.1 0
9 HLA-E 16.0 0
10 S100A9 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.4 14.2 66.5%
2 S100A9 16.0
bar=donor   line=cohort median 		15.8 15.5 79.7%
3 IL1B 9.3
bar=donor   line=cohort median 		8.8 9.3 51.4%
4 CXCL8 12.1
bar=donor   line=cohort median 		12.2 11.4 73.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.1
bar=donor   line=cohort median 		6.1 6.1 89.4%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 74.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.2
bar=donor   line=cohort median 		14.3 14.3 36.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.9
bar=donor   line=cohort median 		10.6 10.4 8.8%
9 CD3E 11.6
bar=donor   line=cohort median 		12.1 12.0 3.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.3
bar=donor   line=cohort median 		10.8 10.9 4.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		12.2 11.7 55.0%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 55.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 53.2%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.6 15.3 37.8%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 48.2%
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