GSM8077660

Dataset: gse255685 • Sample: Z584 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 35.3%ile (≈ Median)
22,384 Genes with score > 0 Group median: 22,381 • 59.9%ile (≈ Median)
0 Median expression score Group median: 0 • 50.0%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.88
bar=donor   line=cohort median 		2.02 26.7%
FOXO3 Insulin/IGF-1 Signaling 10.14
bar=donor   line=cohort median 		9.99 75.5%
CETP Lipid Metabolism 4.55
bar=donor   line=cohort median 		5.05 2.3%
SIRT6 Sirtuin Family 8.24
bar=donor   line=cohort median 		8.34 26.7%
SIRT1 Sirtuin Family 8.64
bar=donor   line=cohort median 		8.72 41.4%
SIRT3 Sirtuin Family 7.36
bar=donor   line=cohort median 		7.49 26.7%
IGF1R Insulin/IGF-1 Signaling 9.81
bar=donor   line=cohort median 		10.21 17.0%
KLOTHO Anti-aging 2.63
bar=donor   line=cohort median 		2.51 67.6%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 42.1%
IL6 Inflammation 1.57
bar=donor   line=cohort median 		1.16 94.1%
TERT Telomere Maintenance 1.45
bar=donor   line=cohort median 		1.51 37.8%
IRS2 Insulin/IGF-1 Signaling 10.14
bar=donor   line=cohort median 		9.81 70.4%
TP53 Tumor Suppression 8.66
bar=donor   line=cohort median 		8.92 21.3%
SHC1 Signal Transduction 9.50
bar=donor   line=cohort median 		9.35 86.9%
ACE Signal Transduction 4.68
bar=donor   line=cohort median 		4.64 52.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 EEF1A1 17.0 0
3 B2M 16.9 0
4 MT-CO1 16.8 0
5 ACTB 16.7 0
6 MT-RNR1 16.1 0
7 HLA-C 16.0 0
8 HLA-B 15.9 0
9 MT-ND4 15.8 0
10 HLA-E 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.8
bar=donor   line=cohort median 		14.4 14.2 27.4%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 42.5%
3 IL1B 8.3
bar=donor   line=cohort median 		8.8 9.3 10.9%
4 CXCL8 12.6
bar=donor   line=cohort median 		12.2 11.4 84.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.6
bar=donor   line=cohort median 		6.1 6.1 13.8%
6 FCGR3B 14.2
bar=donor   line=cohort median 		14.7 14.7 15.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 88.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.5
bar=donor   line=cohort median 		10.6 10.4 64.3%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 62.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.8 10.9 33.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.6
bar=donor   line=cohort median 		12.2 11.7 90.9%
12 GNLY 12.8
bar=donor   line=cohort median 		12.4 12.1 87.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.8
bar=donor   line=cohort median 		16.5 16.4 94.4%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 86.2%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 72.6%
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