GSM8077661

Dataset: gse255685 • Sample: Z585 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 23.1%ile (↓ Low)
22,362 Genes with score > 0 Group median: 22,381 • 29.0%ile (≈ Median)
0 Median expression score Group median: 0 • 29.6%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.02
bar=donor   line=cohort median 		2.02 49.6%
FOXO3 Insulin/IGF-1 Signaling 10.12
bar=donor   line=cohort median 		9.99 72.6%
CETP Lipid Metabolism 4.54
bar=donor   line=cohort median 		5.05 2.0%
SIRT6 Sirtuin Family 8.21
bar=donor   line=cohort median 		8.34 21.7%
SIRT1 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.72 51.4%
SIRT3 Sirtuin Family 7.40
bar=donor   line=cohort median 		7.49 35.0%
IGF1R Insulin/IGF-1 Signaling 9.88
bar=donor   line=cohort median 		10.21 23.5%
KLOTHO Anti-aging 2.89
bar=donor   line=cohort median 		2.51 90.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 8.8%
IL6 Inflammation 1.37
bar=donor   line=cohort median 		1.16 84.1%
TERT Telomere Maintenance 1.41
bar=donor   line=cohort median 		1.51 26.0%
IRS2 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.81 68.3%
TP53 Tumor Suppression 8.71
bar=donor   line=cohort median 		8.92 28.1%
SHC1 Signal Transduction 9.53
bar=donor   line=cohort median 		9.35 90.5%
ACE Signal Transduction 4.59
bar=donor   line=cohort median 		4.64 46.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 EEF1A1 17.0 0
3 B2M 17.0 0
4 ACTB 16.6 0
5 MT-CO1 16.6 0
6 HLA-C 16.0 0
7 MT-RNR1 16.0 0
8 HLA-E 15.8 0
9 HLA-B 15.8 0
10 MT-ND4 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.0
bar=donor   line=cohort median 		14.4 14.2 40.0%
2 S100A9 15.5
bar=donor   line=cohort median 		15.8 15.5 51.4%
3 IL1B 8.7
bar=donor   line=cohort median 		8.8 9.3 24.9%
4 CXCL8 13.3
bar=donor   line=cohort median 		12.2 11.4 95.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.1 6.1 43.9%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.7 14.7 28.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.2
bar=donor   line=cohort median 		14.3 14.3 99.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.6 10.4 61.5%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 43.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.8 10.9 37.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.4
bar=donor   line=cohort median 		12.2 11.7 85.5%
12 GNLY 12.7
bar=donor   line=cohort median 		12.4 12.1 83.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 83.7%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.6 15.3 75.8%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 45.7%
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