GSM8077662

Dataset: gse255685 • Sample: Z588 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 99.1%ile (↑ High)
22,438 Genes with score > 0 Group median: 22,381 • 95.0%ile (↑ High)
0 Median expression score Group median: 0 • 93.4%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

63.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.51
bar=donor   line=cohort median 		2.02 94.1%
FOXO3 Insulin/IGF-1 Signaling 10.61
bar=donor   line=cohort median 		9.99 98.4%
CETP Lipid Metabolism 4.75
bar=donor   line=cohort median 		5.05 16.3%
SIRT6 Sirtuin Family 8.36
bar=donor   line=cohort median 		8.34 57.5%
SIRT1 Sirtuin Family 8.83
bar=donor   line=cohort median 		8.72 73.7%
SIRT3 Sirtuin Family 7.34
bar=donor   line=cohort median 		7.49 23.5%
IGF1R Insulin/IGF-1 Signaling 10.72
bar=donor   line=cohort median 		10.21 96.2%
KLOTHO Anti-aging 2.68
bar=donor   line=cohort median 		2.51 74.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 24.9%
IL6 Inflammation 1.68
bar=donor   line=cohort median 		1.16 96.2%
TERT Telomere Maintenance 1.69
bar=donor   line=cohort median 		1.51 83.7%
IRS2 Insulin/IGF-1 Signaling 10.89
bar=donor   line=cohort median 		9.81 95.5%
TP53 Tumor Suppression 8.64
bar=donor   line=cohort median 		8.92 18.8%
SHC1 Signal Transduction 9.47
bar=donor   line=cohort median 		9.35 81.5%
ACE Signal Transduction 4.31
bar=donor   line=cohort median 		4.64 17.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.0 0
3 EEF1A1 16.7 0
4 ACTB 16.5 0
5 HLA-C 16.3 0
6 MT-CO1 16.2 0
7 HLA-B 16.0 0
8 HLA-E 15.9 0
9 MT-RNR1 15.8 0
10 S100A9 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.4 14.2 64.0%
2 S100A9 15.8
bar=donor   line=cohort median 		15.8 15.5 69.4%
3 IL1B 9.1
bar=donor   line=cohort median 		8.8 9.3 41.4%
4 CXCL8 13.3
bar=donor   line=cohort median 		12.2 11.4 95.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 40.3%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 65.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 33.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.0
bar=donor   line=cohort median 		10.6 10.4 12.7%
9 CD3E 11.6
bar=donor   line=cohort median 		12.1 12.0 5.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.8 10.9 92.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.2
bar=donor   line=cohort median 		12.2 11.7 12.7%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 60.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.5 16.4 10.6%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.6 15.3 36.0%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.3 15.2 28.5%
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