GSM8077663

Dataset: gse255685 • Sample: Z589 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 60.8%ile (≈ Median)
22,378 Genes with score > 0 Group median: 22,381 • 50.0%ile (≈ Median)
0 Median expression score Group median: 0 • 62.2%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

56.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.65
bar=donor   line=cohort median 		2.02 97.0%
FOXO3 Insulin/IGF-1 Signaling 10.16
bar=donor   line=cohort median 		9.99 78.0%
CETP Lipid Metabolism 5.02
bar=donor   line=cohort median 		5.05 46.1%
SIRT6 Sirtuin Family 8.58
bar=donor   line=cohort median 		8.34 85.5%
SIRT1 Sirtuin Family 8.56
bar=donor   line=cohort median 		8.72 26.7%
SIRT3 Sirtuin Family 7.39
bar=donor   line=cohort median 		7.49 32.8%
IGF1R Insulin/IGF-1 Signaling 10.37
bar=donor   line=cohort median 		10.21 69.0%
KLOTHO Anti-aging 2.28
bar=donor   line=cohort median 		2.51 15.6%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 63.6%
IL6 Inflammation 1.68
bar=donor   line=cohort median 		1.16 97.0%
TERT Telomere Maintenance 1.48
bar=donor   line=cohort median 		1.51 43.2%
IRS2 Insulin/IGF-1 Signaling 10.47
bar=donor   line=cohort median 		9.81 82.6%
TP53 Tumor Suppression 8.52
bar=donor   line=cohort median 		8.92 10.9%
SHC1 Signal Transduction 9.41
bar=donor   line=cohort median 		9.35 67.9%
ACE Signal Transduction 4.44
bar=donor   line=cohort median 		4.64 30.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.9 0
2 B2M 17.3 0
3 EEF1A1 17.2 0
4 ACTB 16.8 0
5 MT-CO1 16.4 0
6 HLA-B 16.4 0
7 MT-RNR1 16.3 0
8 HLA-C 16.3 0
9 S100A9 16.1 0
10 HLA-E 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		14.4 14.2 71.5%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 83.3%
3 IL1B 9.0
bar=donor   line=cohort median 		8.8 9.3 35.7%
4 CXCL8 13.6
bar=donor   line=cohort median 		12.2 11.4 97.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 33.5%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 38.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.3 14.3 54.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 76.2%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 85.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.5
bar=donor   line=cohort median 		10.8 10.9 15.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.5
bar=donor   line=cohort median 		12.2 11.7 88.4%
12 GNLY 13.0
bar=donor   line=cohort median 		12.4 12.1 91.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 42.5%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 93.0%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 91.9%
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