GSM8077664

Dataset: gse255685 • Sample: Z590 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 90.5%ile (↑ High)
22,405 Genes with score > 0 Group median: 22,381 • 78.3%ile (↑ High)
0 Median expression score Group median: 0 • 70.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

49.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.05
bar=donor   line=cohort median 		2.02 54.7%
FOXO3 Insulin/IGF-1 Signaling 10.25
bar=donor   line=cohort median 		9.99 86.6%
CETP Lipid Metabolism 4.55
bar=donor   line=cohort median 		5.05 2.7%
SIRT6 Sirtuin Family 8.39
bar=donor   line=cohort median 		8.34 62.2%
SIRT1 Sirtuin Family 8.32
bar=donor   line=cohort median 		8.72 7.0%
SIRT3 Sirtuin Family 7.65
bar=donor   line=cohort median 		7.49 79.0%
IGF1R Insulin/IGF-1 Signaling 9.93
bar=donor   line=cohort median 		10.21 26.3%
KLOTHO Anti-aging 2.63
bar=donor   line=cohort median 		2.51 68.3%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 93.0%
IL6 Inflammation 1.18
bar=donor   line=cohort median 		1.16 56.8%
TERT Telomere Maintenance 1.35
bar=donor   line=cohort median 		1.51 14.2%
IRS2 Insulin/IGF-1 Signaling 10.21
bar=donor   line=cohort median 		9.81 72.6%
TP53 Tumor Suppression 8.68
bar=donor   line=cohort median 		8.92 24.2%
SHC1 Signal Transduction 9.50
bar=donor   line=cohort median 		9.35 86.6%
ACE Signal Transduction 4.25
bar=donor   line=cohort median 		4.64 12.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.0 0
2 B2M 17.3 0
3 EEF1A1 17.3 0
4 ACTB 17.0 0
5 FTL 16.7 0
6 HLA-C 16.5 0
7 MT-CO1 16.5 0
8 MT-RNR1 16.4 0
9 HLA-B 16.3 0
10 UBA52 16.3 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.7
bar=donor   line=cohort median 		14.4 14.2 80.8%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 86.2%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 27.8%
4 CXCL8 12.9
bar=donor   line=cohort median 		12.2 11.4 91.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.1
bar=donor   line=cohort median 		6.1 6.1 88.4%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 42.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.3
bar=donor   line=cohort median 		14.3 14.3 48.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.6 10.4 86.6%
9 CD3E 12.3
bar=donor   line=cohort median 		12.1 12.0 91.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 55.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.4
bar=donor   line=cohort median 		12.2 11.7 85.8%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 57.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 74.0%
17 MT-CO2 15.9
bar=donor   line=cohort median 		15.6 15.3 94.1%
18 MT-ND1 15.7
bar=donor   line=cohort median 		15.3 15.2 94.4%
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