GSM8077665

Dataset: gse255685 • Sample: Z592 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 10.2%ile (↓ Low)
22,370 Genes with score > 0 Group median: 22,381 • 38.9%ile (≈ Median)
0 Median expression score Group median: 0 • 29.9%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.89
bar=donor   line=cohort median 		2.02 29.6%
FOXO3 Insulin/IGF-1 Signaling 9.63
bar=donor   line=cohort median 		9.99 8.8%
CETP Lipid Metabolism 5.06
bar=donor   line=cohort median 		5.05 51.4%
SIRT6 Sirtuin Family 8.42
bar=donor   line=cohort median 		8.34 65.4%
SIRT1 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.72 51.8%
SIRT3 Sirtuin Family 7.42
bar=donor   line=cohort median 		7.49 36.0%
IGF1R Insulin/IGF-1 Signaling 9.84
bar=donor   line=cohort median 		10.21 19.9%
KLOTHO Anti-aging 2.66
bar=donor   line=cohort median 		2.51 70.4%
APOC3 Lipid Metabolism -2.08
bar=donor   line=cohort median 		-2.11 96.6%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 9.9%
TERT Telomere Maintenance 1.38
bar=donor   line=cohort median 		1.51 21.7%
IRS2 Insulin/IGF-1 Signaling 9.62
bar=donor   line=cohort median 		9.81 31.4%
TP53 Tumor Suppression 9.26
bar=donor   line=cohort median 		8.92 95.9%
SHC1 Signal Transduction 9.30
bar=donor   line=cohort median 		9.35 30.3%
ACE Signal Transduction 4.06
bar=donor   line=cohort median 		4.64 3.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 EEF1A1 17.0 0
3 MT-CO1 16.9 0
4 B2M 16.9 0
5 ACTB 16.8 0
6 MT-RNR1 16.4 0
7 HLA-C 16.3 0
8 MT-ND4 16.1 0
9 MT-CO2 15.9 0
10 HLA-B 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.0
bar=donor   line=cohort median 		14.4 14.2 42.1%
2 S100A9 15.5
bar=donor   line=cohort median 		15.8 15.5 50.0%
3 IL1B 9.0
bar=donor   line=cohort median 		8.8 9.3 35.3%
4 CXCL8 11.5
bar=donor   line=cohort median 		12.2 11.4 52.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.6
bar=donor   line=cohort median 		6.1 6.1 13.4%
6 FCGR3B 13.7
bar=donor   line=cohort median 		14.7 14.7 2.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 32.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.6 10.4 82.3%
9 CD3E 12.3
bar=donor   line=cohort median 		12.1 12.0 89.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		10.8 10.9 78.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.6
bar=donor   line=cohort median 		12.2 11.7 91.6%
12 GNLY 13.0
bar=donor   line=cohort median 		12.4 12.1 92.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.9
bar=donor   line=cohort median 		16.5 16.4 97.7%
17 MT-CO2 15.9
bar=donor   line=cohort median 		15.6 15.3 94.4%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 92.3%
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