GSM8077666

Dataset: gse255685 • Sample: Z595 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 31.0%ile (≈ Median)
22,360 Genes with score > 0 Group median: 22,381 • 26.0%ile (≈ Median)
0 Median expression score Group median: 0 • 18.8%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

42.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.95
bar=donor   line=cohort median 		2.02 38.9%
FOXO3 Insulin/IGF-1 Signaling 9.71
bar=donor   line=cohort median 		9.99 15.6%
CETP Lipid Metabolism 5.45
bar=donor   line=cohort median 		5.05 89.1%
SIRT6 Sirtuin Family 8.68
bar=donor   line=cohort median 		8.34 91.2%
SIRT1 Sirtuin Family 8.41
bar=donor   line=cohort median 		8.72 12.7%
SIRT3 Sirtuin Family 7.64
bar=donor   line=cohort median 		7.49 75.8%
IGF1R Insulin/IGF-1 Signaling 9.87
bar=donor   line=cohort median 		10.21 21.3%
KLOTHO Anti-aging 2.57
bar=donor   line=cohort median 		2.51 60.0%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 81.2%
IL6 Inflammation 1.02
bar=donor   line=cohort median 		1.16 15.2%
TERT Telomere Maintenance 1.31
bar=donor   line=cohort median 		1.51 8.8%
IRS2 Insulin/IGF-1 Signaling 9.92
bar=donor   line=cohort median 		9.81 59.0%
TP53 Tumor Suppression 8.68
bar=donor   line=cohort median 		8.92 26.0%
SHC1 Signal Transduction 9.24
bar=donor   line=cohort median 		9.35 13.8%
ACE Signal Transduction 4.40
bar=donor   line=cohort median 		4.64 27.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 17.4 0
3 EEF1A1 16.8 0
4 ACTB 16.8 0
5 HLA-C 16.6 0
6 MT-CO1 16.5 0
7 HLA-B 16.4 0
8 S100A9 16.3 0
9 MT-RNR1 16.3 0
10 HLA-E 16.2 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.9
bar=donor   line=cohort median 		14.4 14.2 88.4%
2 S100A9 16.3
bar=donor   line=cohort median 		15.8 15.5 91.9%
3 IL1B 9.5
bar=donor   line=cohort median 		8.8 9.3 61.1%
4 CXCL8 12.7
bar=donor   line=cohort median 		12.2 11.4 88.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 23.5%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 70.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.0
bar=donor   line=cohort median 		14.3 14.3 26.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.8
bar=donor   line=cohort median 		10.6 10.4 88.4%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 81.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.3
bar=donor   line=cohort median 		10.8 10.9 4.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.7
bar=donor   line=cohort median 		12.2 11.7 93.0%
12 GNLY 13.2
bar=donor   line=cohort median 		12.4 12.1 95.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 55.4%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 87.3%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 88.4%
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