GSM8077668

Dataset: gse255685 • Sample: Z598 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 25.6%ile (≈ Median)
22,345 Genes with score > 0 Group median: 22,381 • 11.6%ile (↓ Low)
0 Median expression score Group median: 0 • 21.7%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.46
bar=donor   line=cohort median 		2.02 91.6%
FOXO3 Insulin/IGF-1 Signaling 9.09
bar=donor   line=cohort median 		9.99 0.2%
CETP Lipid Metabolism 4.74
bar=donor   line=cohort median 		5.05 15.6%
SIRT6 Sirtuin Family 8.84
bar=donor   line=cohort median 		8.34 96.2%
SIRT1 Sirtuin Family 8.01
bar=donor   line=cohort median 		8.72 1.6%
SIRT3 Sirtuin Family 7.73
bar=donor   line=cohort median 		7.49 87.6%
IGF1R Insulin/IGF-1 Signaling 9.29
bar=donor   line=cohort median 		10.21 0.5%
KLOTHO Anti-aging 2.20
bar=donor   line=cohort median 		2.51 9.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 67.6%
IL6 Inflammation 1.20
bar=donor   line=cohort median 		1.16 59.3%
TERT Telomere Maintenance 1.91
bar=donor   line=cohort median 		1.51 97.0%
IRS2 Insulin/IGF-1 Signaling 8.99
bar=donor   line=cohort median 		9.81 0.9%
TP53 Tumor Suppression 9.02
bar=donor   line=cohort median 		8.92 67.2%
SHC1 Signal Transduction 9.07
bar=donor   line=cohort median 		9.35 1.3%
ACE Signal Transduction 4.38
bar=donor   line=cohort median 		4.64 24.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 17.3 0
3 EEF1A1 16.9 0
4 ACTB 16.7 0
5 HLA-C 16.7 0
6 MT-CO1 16.5 0
7 HLA-B 16.2 0
8 TMSB4X 16.1 0
9 MT-RNR1 16.0 0
10 HLA-E 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 54.3%
2 S100A9 15.8
bar=donor   line=cohort median 		15.8 15.5 71.1%
3 IL1B 8.6
bar=donor   line=cohort median 		8.8 9.3 19.9%
4 CXCL8 11.1
bar=donor   line=cohort median 		12.2 11.4 44.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 52.2%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.7 14.7 24.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.2
bar=donor   line=cohort median 		14.3 14.3 0.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.4
bar=donor   line=cohort median 		10.6 10.4 99.5%
9 CD3E 12.5
bar=donor   line=cohort median 		12.1 12.0 96.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.8 10.9 86.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 13.3
bar=donor   line=cohort median 		12.2 11.7 98.7%
12 GNLY 13.9
bar=donor   line=cohort median 		12.4 12.1 99.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 58.6%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 90.9%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 67.6%
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