GSM8077669

Dataset: gse255685 • Sample: Z599 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 1.3%ile (↓ Low)
22,308 Genes with score > 0 Group median: 22,381 • 0.5%ile (↓ Low)
0 Median expression score Group median: 0 • 0.5%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

42.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.22
bar=donor   line=cohort median 		2.02 78.0%
FOXO3 Insulin/IGF-1 Signaling 9.35
bar=donor   line=cohort median 		9.99 0.5%
CETP Lipid Metabolism 5.08
bar=donor   line=cohort median 		5.05 56.1%
SIRT6 Sirtuin Family 8.41
bar=donor   line=cohort median 		8.34 63.6%
SIRT1 Sirtuin Family 8.70
bar=donor   line=cohort median 		8.72 47.5%
SIRT3 Sirtuin Family 7.55
bar=donor   line=cohort median 		7.49 59.3%
IGF1R Insulin/IGF-1 Signaling 9.41
bar=donor   line=cohort median 		10.21 3.1%
KLOTHO Anti-aging 2.20
bar=donor   line=cohort median 		2.51 8.8%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 66.5%
IL6 Inflammation 1.20
bar=donor   line=cohort median 		1.16 59.0%
TERT Telomere Maintenance 1.30
bar=donor   line=cohort median 		1.51 6.6%
IRS2 Insulin/IGF-1 Signaling 9.64
bar=donor   line=cohort median 		9.81 32.4%
TP53 Tumor Suppression 9.16
bar=donor   line=cohort median 		8.92 88.0%
SHC1 Signal Transduction 9.33
bar=donor   line=cohort median 		9.35 41.4%
ACE Signal Transduction 4.34
bar=donor   line=cohort median 		4.64 19.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 EEF1A1 17.2 0
3 B2M 17.1 0
4 ACTB 16.7 0
5 MT-CO1 16.7 0
6 HLA-C 16.3 0
7 MT-RNR1 16.1 0
8 HLA-B 16.0 0
9 MT-ND4 15.9 0
10 HLA-E 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.6
bar=donor   line=cohort median 		14.4 14.2 20.3%
2 S100A9 15.2
bar=donor   line=cohort median 		15.8 15.5 24.2%
3 IL1B 8.7
bar=donor   line=cohort median 		8.8 9.3 24.2%
4 CXCL8 11.5
bar=donor   line=cohort median 		12.2 11.4 53.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 34.6%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.7 14.7 25.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.0
bar=donor   line=cohort median 		14.3 14.3 19.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.1
bar=donor   line=cohort median 		10.6 10.4 97.3%
9 CD3E 12.7
bar=donor   line=cohort median 		12.1 12.0 98.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.8 10.9 30.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 13.0
bar=donor   line=cohort median 		12.2 11.7 97.7%
12 GNLY 13.2
bar=donor   line=cohort median 		12.4 12.1 97.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.7
bar=donor   line=cohort median 		16.5 16.4 90.9%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 88.0%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 89.4%
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