GSM8077670

Dataset: gse255685 • Sample: Z608 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 14.2%ile (↓ Low)
22,325 Genes with score > 0 Group median: 22,381 • 2.9%ile (↓ Low)
0 Median expression score Group median: 0 • 4.8%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

55.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.97
bar=donor   line=cohort median 		2.02 42.5%
FOXO3 Insulin/IGF-1 Signaling 10.21
bar=donor   line=cohort median 		9.99 84.1%
CETP Lipid Metabolism 5.15
bar=donor   line=cohort median 		5.05 65.8%
SIRT6 Sirtuin Family 8.46
bar=donor   line=cohort median 		8.34 71.9%
SIRT1 Sirtuin Family 9.03
bar=donor   line=cohort median 		8.72 96.6%
SIRT3 Sirtuin Family 7.31
bar=donor   line=cohort median 		7.49 18.8%
IGF1R Insulin/IGF-1 Signaling 10.60
bar=donor   line=cohort median 		10.21 89.1%
KLOTHO Anti-aging 2.65
bar=donor   line=cohort median 		2.51 69.7%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 53.2%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 9.1%
TERT Telomere Maintenance 1.29
bar=donor   line=cohort median 		1.51 3.4%
IRS2 Insulin/IGF-1 Signaling 10.30
bar=donor   line=cohort median 		9.81 78.7%
TP53 Tumor Suppression 8.99
bar=donor   line=cohort median 		8.92 61.1%
SHC1 Signal Transduction 9.53
bar=donor   line=cohort median 		9.35 89.8%
ACE Signal Transduction 4.10
bar=donor   line=cohort median 		4.64 4.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.3 0
3 ACTB 16.9 0
4 EEF1A1 16.8 0
5 MT-CO1 16.4 0
6 HLA-C 16.3 0
7 HLA-B 16.3 0
8 MT-RNR1 16.1 0
9 FTL 16.1 0
10 S100A9 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		14.4 14.2 71.9%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 84.1%
3 IL1B 10.5
bar=donor   line=cohort median 		8.8 9.3 98.0%
4 CXCL8 12.7
bar=donor   line=cohort median 		12.2 11.4 87.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 8.0
bar=donor   line=cohort median 		6.1 6.1 97.3%
6 FCGR3B 15.2
bar=donor   line=cohort median 		14.7 14.7 85.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 86.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.0
bar=donor   line=cohort median 		10.6 10.4 11.6%
9 CD3E 11.6
bar=donor   line=cohort median 		12.1 12.0 4.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 6.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		12.2 11.7 56.1%
12 GNLY 11.8
bar=donor   line=cohort median 		12.4 12.1 26.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 47.5%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 46.4%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 48.9%
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