GSM8077671

Dataset: gse255685 • Sample: Z609 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 34.6%ile (≈ Median)
22,352 Genes with score > 0 Group median: 22,381 • 16.5%ile (↓ Low)
0 Median expression score Group median: 0 • 19.5%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

44.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.98
bar=donor   line=cohort median 		2.02 44.3%
FOXO3 Insulin/IGF-1 Signaling 9.64
bar=donor   line=cohort median 		9.99 9.5%
CETP Lipid Metabolism 5.13
bar=donor   line=cohort median 		5.05 63.3%
SIRT6 Sirtuin Family 8.16
bar=donor   line=cohort median 		8.34 12.4%
SIRT1 Sirtuin Family 8.91
bar=donor   line=cohort median 		8.72 85.8%
SIRT3 Sirtuin Family 7.46
bar=donor   line=cohort median 		7.49 43.9%
IGF1R Insulin/IGF-1 Signaling 9.64
bar=donor   line=cohort median 		10.21 7.7%
KLOTHO Anti-aging 2.46
bar=donor   line=cohort median 		2.51 43.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 16.0%
IL6 Inflammation 1.14
bar=donor   line=cohort median 		1.16 44.6%
TERT Telomere Maintenance 1.83
bar=donor   line=cohort median 		1.51 93.0%
IRS2 Insulin/IGF-1 Signaling 9.87
bar=donor   line=cohort median 		9.81 54.3%
TP53 Tumor Suppression 9.00
bar=donor   line=cohort median 		8.92 62.5%
SHC1 Signal Transduction 9.38
bar=donor   line=cohort median 		9.35 63.3%
ACE Signal Transduction 4.28
bar=donor   line=cohort median 		4.64 14.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 16.8 0
3 EEF1A1 16.6 0
4 ACTB 16.5 0
5 MT-CO1 16.4 0
6 HLA-C 16.1 0
7 MT-RNR1 15.9 0
8 HLA-B 15.7 0
9 MT-ND4 15.6 0
10 HLA-E 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.8
bar=donor   line=cohort median 		14.4 14.2 26.3%
2 S100A9 15.3
bar=donor   line=cohort median 		15.8 15.5 32.1%
3 IL1B 9.3
bar=donor   line=cohort median 		8.8 9.3 45.7%
4 CXCL8 11.4
bar=donor   line=cohort median 		12.2 11.4 50.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 37.5%
6 FCGR3B 14.3
bar=donor   line=cohort median 		14.7 14.7 21.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.3
bar=donor   line=cohort median 		14.3 14.3 45.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.6 10.4 42.5%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 29.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.8 10.9 86.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.5
bar=donor   line=cohort median 		12.2 11.7 39.6%
12 GNLY 11.4
bar=donor   line=cohort median 		12.4 12.1 3.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 48.9%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 66.8%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 44.3%
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