GSM8077672

Dataset: gse255685 • Sample: Z610 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 18.8%ile (↓ Low)
22,361 Genes with score > 0 Group median: 22,381 • 27.4%ile (≈ Median)
0 Median expression score Group median: 0 • 14.5%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.82
bar=donor   line=cohort median 		2.02 18.1%
FOXO3 Insulin/IGF-1 Signaling 9.88
bar=donor   line=cohort median 		9.99 34.6%
CETP Lipid Metabolism 4.82
bar=donor   line=cohort median 		5.05 21.3%
SIRT6 Sirtuin Family 8.33
bar=donor   line=cohort median 		8.34 47.1%
SIRT1 Sirtuin Family 9.00
bar=donor   line=cohort median 		8.72 94.1%
SIRT3 Sirtuin Family 7.33
bar=donor   line=cohort median 		7.49 22.0%
IGF1R Insulin/IGF-1 Signaling 9.96
bar=donor   line=cohort median 		10.21 28.1%
KLOTHO Anti-aging 2.36
bar=donor   line=cohort median 		2.51 27.8%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 6.3%
IL6 Inflammation 1.12
bar=donor   line=cohort median 		1.16 39.3%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 66.9%
IRS2 Insulin/IGF-1 Signaling 10.06
bar=donor   line=cohort median 		9.81 67.2%
TP53 Tumor Suppression 9.01
bar=donor   line=cohort median 		8.92 65.4%
SHC1 Signal Transduction 9.43
bar=donor   line=cohort median 		9.35 75.5%
ACE Signal Transduction 4.14
bar=donor   line=cohort median 		4.64 5.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 16.9 0
3 EEF1A1 16.8 0
4 ACTB 16.5 0
5 MT-CO1 16.5 0
6 HLA-B 15.8 0
7 MT-RNR1 15.8 0
8 HLA-E 15.7 0
9 MT-ND4 15.6 0
10 MT-CO2 15.4 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.7
bar=donor   line=cohort median 		14.4 14.2 21.3%
2 S100A9 15.2
bar=donor   line=cohort median 		15.8 15.5 26.0%
3 IL1B 9.2
bar=donor   line=cohort median 		8.8 9.3 42.5%
4 CXCL8 11.8
bar=donor   line=cohort median 		12.2 11.4 61.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.7
bar=donor   line=cohort median 		6.1 6.1 80.1%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.7 14.7 23.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 27.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.6 10.4 55.7%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 61.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.8 10.9 60.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.3
bar=donor   line=cohort median 		12.2 11.7 84.8%
12 GNLY 12.8
bar=donor   line=cohort median 		12.4 12.1 84.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 65.1%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 65.1%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 46.8%
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