GSM8077673

Dataset: gse255685 • Sample: Z612 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 61.1%ile (≈ Median)
22,373 Genes with score > 0 Group median: 22,381 • 42.8%ile (≈ Median)
0 Median expression score Group median: 0 • 65.4%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.90
bar=donor   line=cohort median 		2.02 31.4%
FOXO3 Insulin/IGF-1 Signaling 9.94
bar=donor   line=cohort median 		9.99 42.8%
CETP Lipid Metabolism 5.23
bar=donor   line=cohort median 		5.05 74.0%
SIRT6 Sirtuin Family 8.37
bar=donor   line=cohort median 		8.34 59.7%
SIRT1 Sirtuin Family 8.91
bar=donor   line=cohort median 		8.72 84.8%
SIRT3 Sirtuin Family 7.33
bar=donor   line=cohort median 		7.49 20.6%
IGF1R Insulin/IGF-1 Signaling 9.98
bar=donor   line=cohort median 		10.21 30.3%
KLOTHO Anti-aging 2.42
bar=donor   line=cohort median 		2.51 36.7%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 57.9%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 10.9%
TERT Telomere Maintenance 1.29
bar=donor   line=cohort median 		1.51 4.1%
IRS2 Insulin/IGF-1 Signaling 9.88
bar=donor   line=cohort median 		9.81 55.7%
TP53 Tumor Suppression 8.92
bar=donor   line=cohort median 		8.92 50.7%
SHC1 Signal Transduction 9.40
bar=donor   line=cohort median 		9.35 67.2%
ACE Signal Transduction 4.61
bar=donor   line=cohort median 		4.64 47.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 16.9 0
3 EEF1A1 16.6 0
4 MT-CO1 16.6 0
5 ACTB 16.6 0
6 HLA-C 16.1 0
7 MT-RNR1 16.1 0
8 HLA-B 15.8 0
9 HLA-E 15.7 0
10 MT-ND4 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.6
bar=donor   line=cohort median 		14.4 14.2 18.5%
2 S100A9 15.0
bar=donor   line=cohort median 		15.8 15.5 16.3%
3 IL1B 9.1
bar=donor   line=cohort median 		8.8 9.3 38.2%
4 CXCL8 11.6
bar=donor   line=cohort median 		12.2 11.4 56.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.3
bar=donor   line=cohort median 		6.1 6.1 65.4%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 66.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.9
bar=donor   line=cohort median 		14.3 14.3 14.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 36.4%
9 CD3E 11.7
bar=donor   line=cohort median 		12.1 12.0 13.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.7
bar=donor   line=cohort median 		10.8 10.9 29.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 72.6%
12 GNLY 12.3
bar=donor   line=cohort median 		12.4 12.1 64.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 84.1%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 57.5%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 44.6%
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