GSM8077675

Dataset: gse255685 • Sample: Z617 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 26.0%ile (≈ Median)
22,366 Genes with score > 0 Group median: 22,381 • 33.9%ile (≈ Median)
0 Median expression score Group median: 0 • 45.3%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.72
bar=donor   line=cohort median 		2.02 2.7%
FOXO3 Insulin/IGF-1 Signaling 10.15
bar=donor   line=cohort median 		9.99 76.9%
CETP Lipid Metabolism 5.07
bar=donor   line=cohort median 		5.05 52.9%
SIRT6 Sirtuin Family 8.10
bar=donor   line=cohort median 		8.34 4.8%
SIRT1 Sirtuin Family 8.75
bar=donor   line=cohort median 		8.72 56.8%
SIRT3 Sirtuin Family 7.33
bar=donor   line=cohort median 		7.49 21.0%
IGF1R Insulin/IGF-1 Signaling 9.78
bar=donor   line=cohort median 		10.21 16.0%
KLOTHO Anti-aging 2.67
bar=donor   line=cohort median 		2.51 70.8%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 56.5%
IL6 Inflammation 1.18
bar=donor   line=cohort median 		1.16 56.5%
TERT Telomere Maintenance 1.69
bar=donor   line=cohort median 		1.51 83.0%
IRS2 Insulin/IGF-1 Signaling 10.61
bar=donor   line=cohort median 		9.81 87.3%
TP53 Tumor Suppression 8.83
bar=donor   line=cohort median 		8.92 42.1%
SHC1 Signal Transduction 9.46
bar=donor   line=cohort median 		9.35 79.8%
ACE Signal Transduction 4.85
bar=donor   line=cohort median 		4.64 72.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.2 0
2 B2M 17.1 0
3 EEF1A1 17.0 0
4 ACTB 16.6 0
5 MT-CO1 16.5 0
6 HLA-C 16.1 0
7 HLA-B 16.1 0
8 FTL 15.9 0
9 HLA-E 15.9 0
10 MT-RNR1 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 47.8%
2 S100A9 15.7
bar=donor   line=cohort median 		15.8 15.5 60.4%
3 IL1B 8.4
bar=donor   line=cohort median 		8.8 9.3 13.4%
4 CXCL8 12.9
bar=donor   line=cohort median 		12.2 11.4 90.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.6
bar=donor   line=cohort median 		6.1 6.1 77.6%
6 FCGR3B 14.5
bar=donor   line=cohort median 		14.7 14.7 32.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.6
bar=donor   line=cohort median 		14.3 14.3 3.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 78.0%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 78.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 9.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.2
bar=donor   line=cohort median 		12.2 11.7 80.5%
12 GNLY 12.9
bar=donor   line=cohort median 		12.4 12.1 89.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 58.2%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 50.4%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.3 15.2 33.9%
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