GSM8077678

Dataset: gse255685 • Sample: Z627 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 13.4%ile (↓ Low)
22,331 Genes with score > 0 Group median: 22,381 • 5.7%ile (↓ Low)
0 Median expression score Group median: 0 • 11.6%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

29.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.91
bar=donor   line=cohort median 		2.02 33.5%
FOXO3 Insulin/IGF-1 Signaling 9.62
bar=donor   line=cohort median 		9.99 6.6%
CETP Lipid Metabolism 4.58
bar=donor   line=cohort median 		5.05 4.5%
SIRT6 Sirtuin Family 8.31
bar=donor   line=cohort median 		8.34 41.4%
SIRT1 Sirtuin Family 8.59
bar=donor   line=cohort median 		8.72 33.2%
SIRT3 Sirtuin Family 7.36
bar=donor   line=cohort median 		7.49 28.5%
IGF1R Insulin/IGF-1 Signaling 9.34
bar=donor   line=cohort median 		10.21 2.0%
KLOTHO Anti-aging 2.19
bar=donor   line=cohort median 		2.51 8.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 64.7%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 12.7%
TERT Telomere Maintenance 1.64
bar=donor   line=cohort median 		1.51 76.9%
IRS2 Insulin/IGF-1 Signaling 9.32
bar=donor   line=cohort median 		9.81 10.2%
TP53 Tumor Suppression 8.91
bar=donor   line=cohort median 		8.92 49.3%
SHC1 Signal Transduction 9.31
bar=donor   line=cohort median 		9.35 37.5%
ACE Signal Transduction 4.52
bar=donor   line=cohort median 		4.64 38.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.1 0
3 EEF1A1 16.8 0
4 ACTB 16.4 0
5 MT-CO1 16.3 0
6 HLA-C 16.2 0
7 HLA-B 15.9 0
8 MT-RNR1 15.9 0
9 HLA-E 15.8 0
10 FTL 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.8
bar=donor   line=cohort median 		14.4 14.2 25.3%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 37.8%
3 IL1B 8.5
bar=donor   line=cohort median 		8.8 9.3 18.8%
4 CXCL8 12.0
bar=donor   line=cohort median 		12.2 11.4 69.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.5
bar=donor   line=cohort median 		6.1 6.1 6.6%
6 FCGR3B 13.8
bar=donor   line=cohort median 		14.7 14.7 5.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.8
bar=donor   line=cohort median 		14.3 14.3 11.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.1
bar=donor   line=cohort median 		10.6 10.4 97.0%
9 CD3E 12.4
bar=donor   line=cohort median 		12.1 12.0 95.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		10.8 10.9 80.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.8
bar=donor   line=cohort median 		12.2 11.7 96.6%
12 GNLY 13.0
bar=donor   line=cohort median 		12.4 12.1 90.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.5 16.4 23.5%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.6 15.3 72.2%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 56.5%
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