GSM8077679

Dataset: gse255685 • Sample: Z629 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 13.8%ile (↓ Low)
22,376 Genes with score > 0 Group median: 22,381 • 46.8%ile (≈ Median)
0 Median expression score Group median: 0 • 36.4%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.19
bar=donor   line=cohort median 		2.02 75.5%
FOXO3 Insulin/IGF-1 Signaling 9.37
bar=donor   line=cohort median 		9.99 0.9%
CETP Lipid Metabolism 5.19
bar=donor   line=cohort median 		5.05 70.8%
SIRT6 Sirtuin Family 8.55
bar=donor   line=cohort median 		8.34 83.0%
SIRT1 Sirtuin Family 8.62
bar=donor   line=cohort median 		8.72 37.8%
SIRT3 Sirtuin Family 7.41
bar=donor   line=cohort median 		7.49 35.7%
IGF1R Insulin/IGF-1 Signaling 9.69
bar=donor   line=cohort median 		10.21 9.5%
KLOTHO Anti-aging 2.07
bar=donor   line=cohort median 		2.51 1.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 31.4%
IL6 Inflammation 1.08
bar=donor   line=cohort median 		1.16 26.7%
TERT Telomere Maintenance 1.65
bar=donor   line=cohort median 		1.51 78.3%
IRS2 Insulin/IGF-1 Signaling 9.19
bar=donor   line=cohort median 		9.81 5.6%
TP53 Tumor Suppression 9.09
bar=donor   line=cohort median 		8.92 77.2%
SHC1 Signal Transduction 9.42
bar=donor   line=cohort median 		9.35 71.9%
ACE Signal Transduction 4.27
bar=donor   line=cohort median 		4.64 14.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 17.1 0
3 EEF1A1 16.9 0
4 ACTB 16.5 0
5 MT-CO1 16.3 0
6 HLA-B 16.3 0
7 HLA-C 16.3 0
8 HLA-E 15.9 0
9 MT-RNR1 15.8 0
10 TMSB4X 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.4 14.2 33.9%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 40.3%
3 IL1B 9.3
bar=donor   line=cohort median 		8.8 9.3 47.1%
4 CXCL8 11.5
bar=donor   line=cohort median 		12.2 11.4 54.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.4
bar=donor   line=cohort median 		6.1 6.1 66.8%
6 FCGR3B 13.8
bar=donor   line=cohort median 		14.7 14.7 5.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.3
bar=donor   line=cohort median 		14.3 14.3 51.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.0
bar=donor   line=cohort median 		10.6 10.4 94.8%
9 CD3E 12.3
bar=donor   line=cohort median 		12.1 12.0 89.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.1
bar=donor   line=cohort median 		10.8 10.9 71.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.7
bar=donor   line=cohort median 		12.2 11.7 94.4%
12 GNLY 12.4
bar=donor   line=cohort median 		12.4 12.1 72.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.5 16.4 24.9%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 45.0%
18 MT-ND1 14.9
bar=donor   line=cohort median 		15.3 15.2 17.7%
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