GSM8077680

Dataset: gse255685 • Sample: Z630 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 49.6%ile (≈ Median)
22,387 Genes with score > 0 Group median: 22,381 • 64.0%ile (≈ Median)
0 Median expression score Group median: 0 • 80.1%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

47.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.43
bar=donor   line=cohort median 		2.02 89.8%
FOXO3 Insulin/IGF-1 Signaling 9.80
bar=donor   line=cohort median 		9.99 24.2%
CETP Lipid Metabolism 4.68
bar=donor   line=cohort median 		5.05 10.6%
SIRT6 Sirtuin Family 8.68
bar=donor   line=cohort median 		8.34 90.9%
SIRT1 Sirtuin Family 8.28
bar=donor   line=cohort median 		8.72 5.9%
SIRT3 Sirtuin Family 7.72
bar=donor   line=cohort median 		7.49 85.8%
IGF1R Insulin/IGF-1 Signaling 9.55
bar=donor   line=cohort median 		10.21 5.9%
KLOTHO Anti-aging 2.42
bar=donor   line=cohort median 		2.51 38.9%
APOC3 Lipid Metabolism -2.04
bar=donor   line=cohort median 		-2.11 98.4%
IL6 Inflammation 1.02
bar=donor   line=cohort median 		1.16 16.7%
TERT Telomere Maintenance 1.42
bar=donor   line=cohort median 		1.51 28.9%
IRS2 Insulin/IGF-1 Signaling 10.79
bar=donor   line=cohort median 		9.81 93.4%
TP53 Tumor Suppression 8.79
bar=donor   line=cohort median 		8.92 37.1%
SHC1 Signal Transduction 9.33
bar=donor   line=cohort median 		9.35 42.5%
ACE Signal Transduction 4.55
bar=donor   line=cohort median 		4.64 41.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.3 0
3 EEF1A1 17.1 0
4 ACTB 16.8 0
5 MT-CO1 16.5 0
6 HLA-B 16.5 0
7 HLA-C 16.4 0
8 FTL 16.3 0
9 MT-RNR1 16.1 0
10 HLA-E 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.4 14.2 62.9%
2 S100A9 16.0
bar=donor   line=cohort median 		15.8 15.5 78.7%
3 IL1B 7.5
bar=donor   line=cohort median 		8.8 9.3 1.3%
4 CXCL8 10.7
bar=donor   line=cohort median 		12.2 11.4 38.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.9
bar=donor   line=cohort median 		6.1 6.1 85.1%
6 FCGR3B 14.3
bar=donor   line=cohort median 		14.7 14.7 22.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 68.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 79.4%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 53.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.3
bar=donor   line=cohort median 		10.8 10.9 3.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 13.2
bar=donor   line=cohort median 		12.2 11.7 98.4%
12 GNLY 12.9
bar=donor   line=cohort median 		12.4 12.1 90.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 75.4%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 93.4%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.3 15.2 73.3%
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