GSM8077681

Dataset: gse255685 • Sample: Z631 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 58.2%ile (≈ Median)
22,383 Genes with score > 0 Group median: 22,381 • 57.9%ile (≈ Median)
0 Median expression score Group median: 0 • 39.2%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.42
bar=donor   line=cohort median 		2.02 89.1%
FOXO3 Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		9.99 17.0%
CETP Lipid Metabolism 4.85
bar=donor   line=cohort median 		5.05 27.8%
SIRT6 Sirtuin Family 8.82
bar=donor   line=cohort median 		8.34 95.9%
SIRT1 Sirtuin Family 8.49
bar=donor   line=cohort median 		8.72 20.3%
SIRT3 Sirtuin Family 7.82
bar=donor   line=cohort median 		7.49 96.2%
IGF1R Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		10.21 12.0%
KLOTHO Anti-aging 2.18
bar=donor   line=cohort median 		2.51 7.0%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 91.9%
IL6 Inflammation 1.18
bar=donor   line=cohort median 		1.16 55.4%
TERT Telomere Maintenance 1.88
bar=donor   line=cohort median 		1.51 95.9%
IRS2 Insulin/IGF-1 Signaling 9.75
bar=donor   line=cohort median 		9.81 43.9%
TP53 Tumor Suppression 8.77
bar=donor   line=cohort median 		8.92 34.6%
SHC1 Signal Transduction 9.43
bar=donor   line=cohort median 		9.35 74.4%
ACE Signal Transduction 4.15
bar=donor   line=cohort median 		4.64 6.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 17.3 0
3 EEF1A1 16.9 0
4 ACTB 16.9 0
5 MT-CO1 16.5 0
6 HLA-C 16.5 0
7 HLA-B 16.5 0
8 FTL 16.3 0
9 MT-RNR1 16.3 0
10 HLA-E 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		14.4 14.2 70.8%
2 S100A9 16.0
bar=donor   line=cohort median 		15.8 15.5 81.5%
3 IL1B 8.9
bar=donor   line=cohort median 		8.8 9.3 32.8%
4 CXCL8 12.8
bar=donor   line=cohort median 		12.2 11.4 89.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.0
bar=donor   line=cohort median 		6.1 6.1 88.0%
6 FCGR3B 13.9
bar=donor   line=cohort median 		14.7 14.7 7.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.6
bar=donor   line=cohort median 		14.3 14.3 3.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.9
bar=donor   line=cohort median 		10.6 10.4 92.3%
9 CD3E 12.3
bar=donor   line=cohort median 		12.1 12.0 91.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 10.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.8
bar=donor   line=cohort median 		12.2 11.7 95.5%
12 GNLY 13.1
bar=donor   line=cohort median 		12.4 12.1 94.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 76.2%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 89.4%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 67.9%
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