GSM8077682

Dataset: gse255685 • Sample: Z632 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 36.0%ile (≈ Median)
22,381 Genes with score > 0 Group median: 22,381 • 55.9%ile (≈ Median)
0 Median expression score Group median: 0 • 31.0%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

52.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.95
bar=donor   line=cohort median 		2.02 39.3%
FOXO3 Insulin/IGF-1 Signaling 9.68
bar=donor   line=cohort median 		9.99 12.4%
CETP Lipid Metabolism 5.01
bar=donor   line=cohort median 		5.05 45.3%
SIRT6 Sirtuin Family 8.52
bar=donor   line=cohort median 		8.34 80.5%
SIRT1 Sirtuin Family 8.63
bar=donor   line=cohort median 		8.72 38.9%
SIRT3 Sirtuin Family 7.71
bar=donor   line=cohort median 		7.49 85.1%
IGF1R Insulin/IGF-1 Signaling 9.71
bar=donor   line=cohort median 		10.21 10.9%
KLOTHO Anti-aging 2.57
bar=donor   line=cohort median 		2.51 59.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 40.3%
IL6 Inflammation 1.17
bar=donor   line=cohort median 		1.16 52.5%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 69.7%
IRS2 Insulin/IGF-1 Signaling 10.09
bar=donor   line=cohort median 		9.81 68.6%
TP53 Tumor Suppression 8.94
bar=donor   line=cohort median 		8.92 53.9%
SHC1 Signal Transduction 9.30
bar=donor   line=cohort median 		9.35 31.4%
ACE Signal Transduction 5.23
bar=donor   line=cohort median 		4.64 95.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.2 0
2 B2M 16.9 0
3 EEF1A1 16.7 0
4 ACTB 16.6 0
5 MT-CO1 16.4 0
6 HLA-C 16.4 0
7 HLA-B 15.8 0
8 HLA-E 15.8 0
9 FTL 15.7 0
10 MT-RNR1 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.4 14.2 32.8%
2 S100A9 15.5
bar=donor   line=cohort median 		15.8 15.5 46.8%
3 IL1B 8.4
bar=donor   line=cohort median 		8.8 9.3 15.6%
4 CXCL8 11.9
bar=donor   line=cohort median 		12.2 11.4 65.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.1 6.1 42.5%
6 FCGR3B 14.5
bar=donor   line=cohort median 		14.7 14.7 36.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.2
bar=donor   line=cohort median 		14.3 14.3 36.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.6 10.4 48.9%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 71.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.8 10.9 85.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.4
bar=donor   line=cohort median 		12.2 11.7 86.9%
12 GNLY 12.8
bar=donor   line=cohort median 		12.4 12.1 86.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 50.4%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 55.0%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.3 15.2 19.2%
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