GSM8077684

Dataset: gse255685 • Sample: Z635 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 93.7%ile (↑ High)
22,405 Genes with score > 0 Group median: 22,381 • 78.3%ile (↑ High)
0 Median expression score Group median: 0 • 71.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

59.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.19
bar=donor   line=cohort median 		2.02 75.1%
FOXO3 Insulin/IGF-1 Signaling 10.63
bar=donor   line=cohort median 		9.99 99.5%
CETP Lipid Metabolism 4.95
bar=donor   line=cohort median 		5.05 38.2%
SIRT6 Sirtuin Family 8.36
bar=donor   line=cohort median 		8.34 55.4%
SIRT1 Sirtuin Family 8.76
bar=donor   line=cohort median 		8.72 58.2%
SIRT3 Sirtuin Family 7.27
bar=donor   line=cohort median 		7.49 13.1%
IGF1R Insulin/IGF-1 Signaling 10.56
bar=donor   line=cohort median 		10.21 86.2%
KLOTHO Anti-aging 2.40
bar=donor   line=cohort median 		2.51 33.2%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 78.7%
IL6 Inflammation 1.47
bar=donor   line=cohort median 		1.16 91.9%
TERT Telomere Maintenance 1.50
bar=donor   line=cohort median 		1.51 48.6%
IRS2 Insulin/IGF-1 Signaling 10.75
bar=donor   line=cohort median 		9.81 91.9%
TP53 Tumor Suppression 8.49
bar=donor   line=cohort median 		8.92 6.3%
SHC1 Signal Transduction 9.35
bar=donor   line=cohort median 		9.35 50.4%
ACE Signal Transduction 4.75
bar=donor   line=cohort median 		4.64 61.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.4 0
3 ACTB 16.8 0
4 EEF1A1 16.6 0
5 S100A9 16.6 0
6 MT-CO1 16.5 0
7 HLA-C 16.4 0
8 HLA-B 16.1 0
9 HLA-E 16.1 0
10 FTL 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.6
bar=donor   line=cohort median 		14.4 14.2 98.4%
2 S100A9 16.6
bar=donor   line=cohort median 		15.8 15.5 96.6%
3 IL1B 10.0
bar=donor   line=cohort median 		8.8 9.3 86.6%
4 CXCL8 12.4
bar=donor   line=cohort median 		12.2 11.4 81.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 51.1%
6 FCGR3B 15.4
bar=donor   line=cohort median 		14.7 14.7 93.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.8
bar=donor   line=cohort median 		14.3 14.3 85.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.0
bar=donor   line=cohort median 		10.6 10.4 10.9%
9 CD3E 11.5
bar=donor   line=cohort median 		12.1 12.0 0.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 8.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.3
bar=donor   line=cohort median 		12.2 11.7 14.9%
12 GNLY 11.6
bar=donor   line=cohort median 		12.4 12.1 13.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 62.9%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.6 15.3 70.1%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.3 15.2 76.5%
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