GSM8077685

Dataset: gse255685 • Sample: Z636 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 81.5%ile (↑ High)
22,410 Genes with score > 0 Group median: 22,381 • 84.1%ile (↑ High)
0 Median expression score Group median: 0 • 71.9%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.23
bar=donor   line=cohort median 		2.02 79.0%
FOXO3 Insulin/IGF-1 Signaling 10.09
bar=donor   line=cohort median 		9.99 65.8%
CETP Lipid Metabolism 4.73
bar=donor   line=cohort median 		5.05 14.9%
SIRT6 Sirtuin Family 8.21
bar=donor   line=cohort median 		8.34 21.0%
SIRT1 Sirtuin Family 8.84
bar=donor   line=cohort median 		8.72 74.4%
SIRT3 Sirtuin Family 7.34
bar=donor   line=cohort median 		7.49 23.8%
IGF1R Insulin/IGF-1 Signaling 10.09
bar=donor   line=cohort median 		10.21 38.2%
KLOTHO Anti-aging 2.29
bar=donor   line=cohort median 		2.51 16.7%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 25.3%
IL6 Inflammation 1.89
bar=donor   line=cohort median 		1.16 99.1%
TERT Telomere Maintenance 1.57
bar=donor   line=cohort median 		1.51 62.5%
IRS2 Insulin/IGF-1 Signaling 10.70
bar=donor   line=cohort median 		9.81 90.5%
TP53 Tumor Suppression 8.60
bar=donor   line=cohort median 		8.92 16.7%
SHC1 Signal Transduction 9.36
bar=donor   line=cohort median 		9.35 56.8%
ACE Signal Transduction 4.10
bar=donor   line=cohort median 		4.64 3.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 17.0 0
3 EEF1A1 17.0 0
4 ACTB 16.4 0
5 MT-CO1 16.2 0
6 HLA-C 15.8 0
7 HLA-B 15.7 0
8 HLA-E 15.6 0
9 MT-RNR1 15.6 0
10 TMSB4X 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.4 14.2 67.6%
2 S100A9 15.5
bar=donor   line=cohort median 		15.8 15.5 48.9%
3 IL1B 9.1
bar=donor   line=cohort median 		8.8 9.3 39.2%
4 CXCL8 14.0
bar=donor   line=cohort median 		12.2 11.4 98.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.9
bar=donor   line=cohort median 		6.1 6.1 96.6%
6 FCGR3B 14.3
bar=donor   line=cohort median 		14.7 14.7 21.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.3 14.3 59.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.5
bar=donor   line=cohort median 		10.6 10.4 67.9%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 34.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.8 10.9 66.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.5
bar=donor   line=cohort median 		12.2 11.7 39.2%
12 GNLY 12.1
bar=donor   line=cohort median 		12.4 12.1 49.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.5 16.4 8.8%
17 MT-CO2 15.0
bar=donor   line=cohort median 		15.6 15.3 15.2%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.3 15.2 23.5%
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