GSM8077686

Dataset: gse255685 • Sample: Z638 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 89.8%ile (↑ High)
22,424 Genes with score > 0 Group median: 22,381 • 91.4%ile (↑ High)
0 Median expression score Group median: 0 • 90.9%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

59.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.11
bar=donor   line=cohort median 		2.02 64.7%
FOXO3 Insulin/IGF-1 Signaling 10.14
bar=donor   line=cohort median 		9.99 75.1%
CETP Lipid Metabolism 5.02
bar=donor   line=cohort median 		5.05 45.7%
SIRT6 Sirtuin Family 8.17
bar=donor   line=cohort median 		8.34 15.2%
SIRT1 Sirtuin Family 8.87
bar=donor   line=cohort median 		8.72 77.6%
SIRT3 Sirtuin Family 7.55
bar=donor   line=cohort median 		7.49 60.4%
IGF1R Insulin/IGF-1 Signaling 10.18
bar=donor   line=cohort median 		10.21 46.1%
KLOTHO Anti-aging 2.52
bar=donor   line=cohort median 		2.51 51.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 17.7%
IL6 Inflammation 1.28
bar=donor   line=cohort median 		1.16 74.0%
TERT Telomere Maintenance 1.79
bar=donor   line=cohort median 		1.51 89.4%
IRS2 Insulin/IGF-1 Signaling 10.85
bar=donor   line=cohort median 		9.81 95.2%
TP53 Tumor Suppression 8.68
bar=donor   line=cohort median 		8.92 26.3%
SHC1 Signal Transduction 9.36
bar=donor   line=cohort median 		9.35 57.2%
ACE Signal Transduction 5.09
bar=donor   line=cohort median 		4.64 90.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.1 0
2 B2M 16.9 0
3 EEF1A1 16.8 0
4 MT-CO1 16.3 0
5 ACTB 16.3 0
6 HLA-C 16.2 0
7 MT-ND4 15.8 0
8 HLA-E 15.7 0
9 TXNIP 15.7 0
10 HLA-B 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.0
bar=donor   line=cohort median 		14.4 14.2 38.5%
2 S100A9 15.3
bar=donor   line=cohort median 		15.8 15.5 33.5%
3 IL1B 8.7
bar=donor   line=cohort median 		8.8 9.3 22.8%
4 CXCL8 12.7
bar=donor   line=cohort median 		12.2 11.4 88.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.4
bar=donor   line=cohort median 		6.1 6.1 3.0%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 65.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.2
bar=donor   line=cohort median 		14.3 14.3 34.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.6 10.4 46.1%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 48.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		10.8 10.9 83.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.7
bar=donor   line=cohort median 		12.2 11.7 48.2%
12 GNLY 12.1
bar=donor   line=cohort median 		12.4 12.1 45.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.5 16.4 19.5%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.6 15.3 25.6%
18 MT-ND1 14.9
bar=donor   line=cohort median 		15.3 15.2 11.6%
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