GSM8077687

Dataset: gse255685 • Sample: Z642 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 57.2%ile (≈ Median)
22,380 Genes with score > 0 Group median: 22,381 • 53.8%ile (≈ Median)
0 Median expression score Group median: 0 • 49.6%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.32
bar=donor   line=cohort median 		2.02 84.4%
FOXO3 Insulin/IGF-1 Signaling 9.92
bar=donor   line=cohort median 		9.99 40.7%
CETP Lipid Metabolism 4.68
bar=donor   line=cohort median 		5.05 10.2%
SIRT6 Sirtuin Family 8.26
bar=donor   line=cohort median 		8.34 30.7%
SIRT1 Sirtuin Family 8.57
bar=donor   line=cohort median 		8.72 29.2%
SIRT3 Sirtuin Family 7.61
bar=donor   line=cohort median 		7.49 70.8%
IGF1R Insulin/IGF-1 Signaling 9.88
bar=donor   line=cohort median 		10.21 22.8%
KLOTHO Anti-aging 2.06
bar=donor   line=cohort median 		2.51 0.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 21.7%
IL6 Inflammation 1.41
bar=donor   line=cohort median 		1.16 87.3%
TERT Telomere Maintenance 1.80
bar=donor   line=cohort median 		1.51 90.5%
IRS2 Insulin/IGF-1 Signaling 10.29
bar=donor   line=cohort median 		9.81 78.0%
TP53 Tumor Suppression 8.79
bar=donor   line=cohort median 		8.92 36.7%
SHC1 Signal Transduction 9.44
bar=donor   line=cohort median 		9.35 76.2%
ACE Signal Transduction 4.04
bar=donor   line=cohort median 		4.64 2.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 EEF1A1 17.0 0
3 B2M 16.9 0
4 ACTB 16.4 0
5 MT-CO1 16.3 0
6 HLA-B 16.0 0
7 HLA-C 15.9 0
8 MT-RNR1 15.8 0
9 HLA-E 15.7 0
10 MT-ND4 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 52.9%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 43.9%
3 IL1B 9.2
bar=donor   line=cohort median 		8.8 9.3 45.0%
4 CXCL8 12.4
bar=donor   line=cohort median 		12.2 11.4 81.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.3
bar=donor   line=cohort median 		6.1 6.1 64.7%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.7 14.7 62.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.2
bar=donor   line=cohort median 		14.3 14.3 39.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.8
bar=donor   line=cohort median 		10.6 10.4 88.0%
9 CD3E 12.3
bar=donor   line=cohort median 		12.1 12.0 90.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.8 10.9 84.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.9
bar=donor   line=cohort median 		12.2 11.7 62.5%
12 GNLY 12.4
bar=donor   line=cohort median 		12.4 12.1 72.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.5 16.4 28.5%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 48.9%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 60.4%
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