GSM8077688

Dataset: gse255685 • Sample: Z644 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 96.2%ile (↑ High)
22,408 Genes with score > 0 Group median: 22,381 • 81.9%ile (↑ High)
0 Median expression score Group median: 0 • 83.0%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

58.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.94
bar=donor   line=cohort median 		2.02 37.8%
FOXO3 Insulin/IGF-1 Signaling 10.36
bar=donor   line=cohort median 		9.99 93.4%
CETP Lipid Metabolism 5.12
bar=donor   line=cohort median 		5.05 62.2%
SIRT6 Sirtuin Family 8.53
bar=donor   line=cohort median 		8.34 81.2%
SIRT1 Sirtuin Family 8.56
bar=donor   line=cohort median 		8.72 27.8%
SIRT3 Sirtuin Family 7.50
bar=donor   line=cohort median 		7.49 51.1%
IGF1R Insulin/IGF-1 Signaling 10.21
bar=donor   line=cohort median 		10.21 51.1%
KLOTHO Anti-aging 2.62
bar=donor   line=cohort median 		2.51 66.5%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 78.0%
IL6 Inflammation 1.68
bar=donor   line=cohort median 		1.16 96.6%
TERT Telomere Maintenance 1.50
bar=donor   line=cohort median 		1.51 48.2%
IRS2 Insulin/IGF-1 Signaling 11.25
bar=donor   line=cohort median 		9.81 98.8%
TP53 Tumor Suppression 8.51
bar=donor   line=cohort median 		8.92 9.9%
SHC1 Signal Transduction 9.39
bar=donor   line=cohort median 		9.35 64.0%
ACE Signal Transduction 4.18
bar=donor   line=cohort median 		4.64 7.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.1 0
3 ACTB 16.7 0
4 EEF1A1 16.7 0
5 MT-CO1 16.5 0
6 HLA-C 16.5 0
7 S100A9 16.3 0
8 MT-RNR1 16.0 0
9 HLA-B 16.0 0
10 FTL 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.2
bar=donor   line=cohort median 		14.4 14.2 96.2%
2 S100A9 16.3
bar=donor   line=cohort median 		15.8 15.5 90.9%
3 IL1B 8.9
bar=donor   line=cohort median 		8.8 9.3 33.2%
4 CXCL8 11.9
bar=donor   line=cohort median 		12.2 11.4 67.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 8.5
bar=donor   line=cohort median 		6.1 6.1 99.1%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.7 14.7 60.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.7
bar=donor   line=cohort median 		14.3 14.3 79.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 30.3%
9 CD3E 11.7
bar=donor   line=cohort median 		12.1 12.0 7.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.5
bar=donor   line=cohort median 		10.8 10.9 13.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		12.2 11.7 60.0%
12 GNLY 12.5
bar=donor   line=cohort median 		12.4 12.1 75.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 67.9%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.6 15.3 80.8%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.3 15.2 81.9%
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