GSM8077689

Dataset: gse255685 • Sample: Z646 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 22.4%ile (↓ Low)
22,362 Genes with score > 0 Group median: 22,381 • 29.0%ile (≈ Median)
0 Median expression score Group median: 0 • 23.1%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

47.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.49
bar=donor   line=cohort median 		2.02 91.9%
FOXO3 Insulin/IGF-1 Signaling 9.67
bar=donor   line=cohort median 		9.99 12.0%
CETP Lipid Metabolism 4.77
bar=donor   line=cohort median 		5.05 17.7%
SIRT6 Sirtuin Family 8.72
bar=donor   line=cohort median 		8.34 92.7%
SIRT1 Sirtuin Family 8.00
bar=donor   line=cohort median 		8.72 1.3%
SIRT3 Sirtuin Family 7.51
bar=donor   line=cohort median 		7.49 52.9%
IGF1R Insulin/IGF-1 Signaling 9.77
bar=donor   line=cohort median 		10.21 15.6%
KLOTHO Anti-aging 2.16
bar=donor   line=cohort median 		2.51 5.2%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 89.8%
IL6 Inflammation 1.15
bar=donor   line=cohort median 		1.16 48.9%
TERT Telomere Maintenance 1.55
bar=donor   line=cohort median 		1.51 57.5%
IRS2 Insulin/IGF-1 Signaling 9.97
bar=donor   line=cohort median 		9.81 62.5%
TP53 Tumor Suppression 8.90
bar=donor   line=cohort median 		8.92 48.9%
SHC1 Signal Transduction 9.46
bar=donor   line=cohort median 		9.35 80.1%
ACE Signal Transduction 4.56
bar=donor   line=cohort median 		4.64 41.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.0 0
2 B2M 17.1 0
3 S100A9 17.0 0
4 ACTB 17.0 0
5 HLA-C 16.9 0
6 EEF1A1 16.9 0
7 MT-CO1 16.7 0
8 MT-RNR1 16.5 0
9 HLA-B 16.4 0
10 FTL 16.4 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.6
bar=donor   line=cohort median 		14.4 14.2 99.1%
2 S100A9 17.0
bar=donor   line=cohort median 		15.8 15.5 98.7%
3 IL1B 9.9
bar=donor   line=cohort median 		8.8 9.3 83.7%
4 CXCL8 13.1
bar=donor   line=cohort median 		12.2 11.4 93.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.8
bar=donor   line=cohort median 		6.1 6.1 83.3%
6 FCGR3B 15.3
bar=donor   line=cohort median 		14.7 14.7 92.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 28.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.6 10.4 81.2%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 78.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 9.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		12.2 11.7 42.5%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 59.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.7
bar=donor   line=cohort median 		16.5 16.4 92.3%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 92.7%
18 MT-ND1 16.0
bar=donor   line=cohort median 		15.3 15.2 98.7%
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