GSM8077690

Dataset: gse255685 • Sample: Z650 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 57.5%ile (≈ Median)
22,392 Genes with score > 0 Group median: 22,381 • 70.3%ile (≈ Median)
0 Median expression score Group median: 0 • 67.6%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

54.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.18
bar=donor   line=cohort median 		2.02 74.7%
FOXO3 Insulin/IGF-1 Signaling 10.17
bar=donor   line=cohort median 		9.99 79.4%
CETP Lipid Metabolism 4.83
bar=donor   line=cohort median 		5.05 25.6%
SIRT6 Sirtuin Family 8.34
bar=donor   line=cohort median 		8.34 49.6%
SIRT1 Sirtuin Family 8.89
bar=donor   line=cohort median 		8.72 81.5%
SIRT3 Sirtuin Family 7.29
bar=donor   line=cohort median 		7.49 15.6%
IGF1R Insulin/IGF-1 Signaling 10.06
bar=donor   line=cohort median 		10.21 36.0%
KLOTHO Anti-aging 2.31
bar=donor   line=cohort median 		2.51 18.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 77.2%
IL6 Inflammation 1.30
bar=donor   line=cohort median 		1.16 76.9%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 67.2%
IRS2 Insulin/IGF-1 Signaling 10.50
bar=donor   line=cohort median 		9.81 83.7%
TP53 Tumor Suppression 8.76
bar=donor   line=cohort median 		8.92 32.8%
SHC1 Signal Transduction 9.37
bar=donor   line=cohort median 		9.35 59.0%
ACE Signal Transduction 4.48
bar=donor   line=cohort median 		4.64 35.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.9 0
2 B2M 17.2 0
3 EEF1A1 16.9 0
4 MT-CO1 16.5 0
5 ACTB 16.4 0
6 MT-RNR1 16.4 0
7 HLA-B 16.0 0
8 MT-ND4 16.0 0
9 HLA-C 15.9 0
10 FTL 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.6
bar=donor   line=cohort median 		14.4 14.2 74.0%
2 S100A9 15.6
bar=donor   line=cohort median 		15.8 15.5 54.7%
3 IL1B 8.6
bar=donor   line=cohort median 		8.8 9.3 19.5%
4 CXCL8 12.6
bar=donor   line=cohort median 		12.2 11.4 85.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 31.4%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 46.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.3 14.3 56.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.5
bar=donor   line=cohort median 		10.6 10.4 62.9%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 52.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.5
bar=donor   line=cohort median 		10.8 10.9 96.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		12.2 11.7 57.5%
12 GNLY 12.4
bar=donor   line=cohort median 		12.4 12.1 69.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 77.2%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.6 15.3 81.2%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.3 15.2 84.4%
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